Browsing Fen Bilimleri Enstitüsü by Issue Date
Now showing items 61-80 of 155
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Akciğer Havayolu Modellemesine Yönelik Oluşturulan Deselülerize Doku İskeleleri ile 3b Hücre Kültür Sistemlerinin Kurulması
(Fen Bilimleri Enstitüsü, 2021)The lungs have the task of providing the necessary oxygen for the cells and carrying out the carbon dioxide formed as a result of metabolic events. During this process, which we call breathing, the lungs encounter many ... -
Hücresizleştirilmiş Sığır Gözü Kası ve Pclkas Matriksi Kompozit Doku İskeleleriyle Göz Kası Rejenerasyonu
(Fen Bilimleri Enstitüsü, 2021)This study has been financially supported by TÜBİTAK under the project named "Extraocular Muscle Regeneration by Decellurized Bovine Extraocular Muscle and PCL-Extraocular Muscle Matrix Composite Tissue Skeleton" (1002 ... -
Biyobozunur Plastik Polihidroksialkanoatların Bacillus Megaterium’da Genetik Mühendisliği Yoluyla Üretiminin Artırılması
(Fen Bilimleri Enstitüsü, 2021)Fossil fuel-derived plastic materials, have currently production and consumption values at increasing quantities, due to their lightness, easy malleability and economical reasons. Owing to their poor degradation rates and ... -
Kıkırdak Doku Mühendisliği için Nanopartikül / Hidrojel Bazlı Kompozit Yapıların Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)Bioactive structures with unique biophysical and chemical properties of nanoparticles give great hope for the future development of tissue engineering applications. The purpose of this study to develop gelatin methacrylate ... -
Türkiye’de Elektrikli Araçların Orta Gerilim Dağıtım Şebekesine Etkisinin Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2021)In one of the major cities in Turkey, the impacts of electric vehicles were examined on medium voltage distribution grid that includes 36 power transformers by using Digsilent PowerFactory software with SCADA data. For ... -
Kornea Doku Mühendisliği İçin Hibrit Biyomateryal Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)The cornea is a transparent structure that covers 1/6 of the eye, has a convex shape, has the task of focusing light and protecting the eye from external influences, and has a major role in vision. Corneal blindness; It ... -
Tetrasiklin Tayinine Yönelik Aptamer Bağlı Peroksidaz Benzeri Mikropartiküllerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)Sensitive and selective methods are needed for the determination of antibiotic residues accumulated in food and water sources to protect human safety and health. Traditional methods used for determination of tetracycline ... -
Gıda Örneklerindeki Benzil Penisilin Hassas Tayinine Yönelik Moleküler Baskılanmış Polimer Temelli Optik Sensörlerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)Penicillin is one of the most commonly used beta antibiotics and has long been widely used in the treatment of various bacterial infections in humans, livestock, poultry and aquaculture. Therefore, the detection of these ... -
Yüksek Sıcaklık Proseslerinin, Silisyum Tabanlı Fotodedektör Aygıt Performansına Etkilerinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2021)The goal of this thesis work is to produce photodetectors in P-I-N form by silicon substrate and to investigate effect of thermal oxidation and doping high temperature microfabrication steps of manufacturing levels of these ... -
Centella Asıatıca Bitki Özütü ile Kaplı Gümüş Nanopartikül İçeren Polimer Liflerin Yara İyileştirici Etkisinin in Vitro ve in Vivo Araştırılması
(Fen Bilimleri Enstitüsü, 2021)In this study, we synthesized functional silver nanoparticles (AgNPs) from silver ions using the therapeutic plant extract of Centella asiatica (CA). The formation of AgNPs coated with CA functional groups (CA-AgNPs) is ... -
Deselülerize Miyokard-Elastomer Yamaların Hazırlanması ve In Vitro Performanslarının İncelenmesi
(Fen Bilimleri Enstitüsü, 2021)Heart failure is the final stage of most cardiovascular diseases, such as myocardial infarction. Unlike other tissues such as bone and skin, heart tissue does not have the ability to regenerate and repair itself. This ... -
Synthesis and Characterization of SbSe Thin Films for Photovoltaic Applications
(Fen Bilimleri Enstitüsü, 2021)In this thesis study, synthesis and characterization of an alternative absorber, antimony selenide (Sb2Se3), layer for photovoltaic applications have been investigated. Synthesis of the Sb2Se3 thin films has been carried ... -
Menisküs Doku Mühendisliği İçin Hibrit Doku İskelelerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)Treatment of meniscal tears that occur as aging, injuries, and various traumas is one of the most performed in orthopedic surgery. The increasing rate of meniscal injuries indicates the urgent need to develop an effective ... -
Antitrombojenik Nanokompozit Kalp Kapakçık Malzemelerinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)The aim of the thesis is to develop composite scaffolds with antithrombogenic properties and high blood compatibility by modifying decellularized pericardial tissue with carboxylated carbon nanotubes and to characterize ... -
Trikalsiyum Fosfata Bağlanmış Mezenkimal Kök Hücre Eksozomlarının Kemik Yenilenmesine
(Fen Bilimleri Enstitüsü, 2021)The structure and functions of bone may be impaired with metabolic-diseases such as osteoporosis, necrotic or traumatic damages, although it is a dynamic tissue that can renew itself under physiological conditions. Critical ... -
İn Vitro Diyagnostik Sistemlerde Kullanılmak Üzere Yeni Nesil Elektrotların Tasarımı ve Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)This study aims to fabricate electrodes with properties of both gold and diamond-like carbon (DLC) thin films for in vitro diagnostic system applications for the first time. A specific self-assembly method was used to ... -
Hücre Ölüm Yolaklarının Tespiti İçin Kağıt Tabanlı Biyosensör Tasarımı
(Fen Bilimleri Enstitüsü, 2021)The aim of the presented thesis, a paper-based biosensor design has been designed to be used in the detection of early (extrinsic pathway) and late (instrinsic pathway) stages of apoptosis. In the study, in order to ... -
İlaç Araştırmaları İçin 3-Boyutlu Mikroakışkan Damar Modelinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)There is a need for a 3-dimensional (3D) vessel model that can be used to simulate in vivo vessel physiology, anatomy, and blood flow-induced fluid tension force that can be used in the investigation of vascular diseases, ... -
Antibakteriyel Aljinat Mikrobaloncuk Yapıların Mikroakışkan Sistemle Hazırlanması
(Fen Bilimleri Enstitüsü, 2021)Microbubbles produced with microfluidic systems have been used as contrast agents in ultrasound radiography for approximately 30 years. In recent years, it has been successfully used in different biomedical applications ... -
Tükürükte Eroin ve Metabolitlerinin Toksikolojik Analizinde Yeni Bir Analitik Gereç Olarak Yüzey Zenginleştirilmiş Raman Spektroskopi
(Fen Bilimleri Enstitüsü, 2021-02-19)Heroin can be detected and quantified by certain analytical methods; however, forensic professionals and criminal laboratories study for cheaper and faster detection tools. Surface-enhanced Raman spectroscopy rise as a ...