Yayıncı "Amer Assoc Cancer Research" Fen Fakültesi için listeleme

Toplam kayıt 2, listelenen: 1-2

    • Rational Drug Redesign to Overcome Drug Resistance in Cancer Therapy: Imatinib Moving Target 

      Fernandez, Ariel; Sanguino, Angela; Peng, Zhenghong; Crespo, Alejandro; Ozturk, Eylem; Zhang, Xi; Wang, Shimei; Bornmann, William; Lopez-Berestein, Gabriel (Amer Assoc Cancer Research, 2007)
      Protein kinases are central targets for drug-based cancer treatment. To avoid functional impairment, the cell develops mechanisms of drug resistance, primarily based on adaptive mutations. Redesigning a drug to target a ...

    • Sustained Adrenergic Signaling Promotes Intratumoral Innervation Through Bdnf Induction 

      Allen, Julie K.; Armaiz-Pena, Guillermo N.; Nagaraja, Archana S.; Özcan, Merve (Amer Assoc Cancer Research, 2018)
      Mounting clinical and preclinical evidence supports a key role for sustained adrenergic signaling in the tumor microenvironment as a driver of tumor growth and progression. However, the mechanisms by which adrenergic ...