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Kolorektal Kanser Metastazlarının Tedavisinde Radyofrekans Ablasyon: Uzun Dönem Klinik Sonuçları
(Tıp Fakültesi, 2013)
Radiofrequency Ablation in the Management of Colorectal cancer metastasis: Long term outcomes. Hacettepe University, School of Medicine, Department of Radiology. Thesis. Ankara. 2013 Radiofrequency ablation (RFA), one of ...
Desmin Geni C.1289-2a>G Mutasyonunun Desmin Proteinine Etkisinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2012)
Autosomal recessive limb girdle muscular dystrophy (LGMD2) is clinically and genetically heterogeneous group of diseases that are characterized by progressive atrophy and weakness of proximal muscles. Two siblings of a ...
Mikrodizilim Gen İfade Çalışmalarında Genelleştirme Yöntemlerinin Regresyon Modelleri Üzerine Etkisi.
(Sağlık Bilimleri Enstitüsü, 2014)
The presence of thousands of gene data belonging to a few number of patients in genetic researches leads to problems in the use of classical statistical methods (linear regression analysis etc.). However, analysis of large ...
Mycobacterium Tuberculosis Klinik İzolatlarında İlaç Direncinin Multipleks Real-Time Pcr Yöntemiyle Saptanması
(Sağlık Bilimleri Enstitüsü, 2013)
Tuberculosis (TB) is stil one of the most serious threats to human health around the world. Increasing of the drug resistance is one of the main cause of this state. Early diagnosis of drug-resistant TB cases is urgently ...
Fare Miyoblast Hücre Hattında KLF5 Geninin Farklılaşma Sürecine Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2014)
Embryonic development of the skeletal muscle and injury repair share several molecular events such as the myogenic regulatory factors (MRFs) and paired-homeobox transcription factors. Myogenesis is a highly regulated complex ...
Muhtemel Otoimmün Lenfoproliferatif Sendrom (Alps) Tanısıyla Izlenen Hastaların Bilinen Moleküler Defektler Yönünden Araştırılması
(Çocuk Sağlığı Enstitüsü, 2014)
Apoptosis plays a crucial role in immune
homeostasis. The interaction between Fas and FasL, essential molecules in an
apoptosis pathway, play an important role in the termination of the immune response,
regulation of ...
Demir Birikimine Bağlı Yetmezlik Gelişen Endokrin Organların T2 Ve T2* Değerlerinin Belirlenmesi
(Tıp Fakültesi, 2013)
The purpose of this study at first stage is to determine the normal R2/T2 for thyroid and pituitary gland, and R2*/T2* values for pancreas, and then at the second stage to evaluate if there is any difference between tl ...
Çocukluk Dönemi Steroide Dirençli Nefrotik Sendroma Sebep Olan Yeni Genlerin Bulunması
(Sağlık Bilimleri Enstitüsü, 2012)
Steroid resistant nephrotic syndrome (SRNS), despite being a rare disease, is the second most common cause of end stage kidney failure in childhood and early adulthood. However the heterogeneity and rarity (<1%) of disease ...
Gitarist Olmayan Bestecilere Klasik Gitarın Teknik ve Müzik Özelliklerinin Tanıtılmasına Yönelik Model Önerisi
(Güzel Sanatlar Enstitüsü, 2013)
In this study, the researcher has tried to explain classical guitar s idiomatic figures in writing and technical qualities to non-guitarist composers.In the first stage, it is attempted to verify the lack of information, ...
Beethoven'ın Erken Dönem Piyano Sonatlarında Gelişme Bölümlerinin Tematik Analizi
(Sosyal Bilimler Enstitüsü, 2014)
This study is an analytical examination of the thematic structure of Development sections of first movements of Ludwig van Beethoven s early piano sonatas. In the Introduction; general structure of the Sonata form, general ...
Franz Liszt Dante Sonatı'nın İncelenmesi
(Güzel Sanatlar Enstitüsü, 2014)
In this thesis Franz Liszt Dante Sonata has been taken in aspect of music history and his life. Life of composer has been examinated elaborately and his relation with the piano was considered form the view of musical history.
Franz Liszt'in Mi Bemol Majör I. Piyano Konçertosunun İncelenmesi
(Güzel Sanatlar Enstitüsü, 2015)
Liszt`s First Piano Concert (E flat Major) takes important place among Liszt`s piano works. Comparing this concert with concerts of composers before Lisztwe can see an important difference in composing stile, music form ...
Cazda Akor Yürüyüşleri Tarihi
(Sosyal Bilimler Enstitüsü, 2013)
In this study, jazz chord progressions have been examined from a historical perspective; and the changes in jazz chord progressions which are in between early jazz and free jazz have been covered. Chord progressions, which ...
Romberg'den Klengel'e 19. Yüzyıl Alman Viyolonsel Okulunda Besteci Viyolonselciler ve 20. Yüzyıl Viyolonselcilerine Etkileri
(Sosyal Bilimler Enstitüsü, 2014)
Until the nineteenth century, the violoncello was primarily considered as background accompaniment instrument. The answer to how the cello was emancipated from its ties to the bass line is found in Dresden, Germany. A group ...
Diabetes Mellitus ve Kronik Periodontitisin Dişeti Dokularında Antimikrobiyal Peptid Ekspresyonu Üzerine Etkileri
(Sağlık Bilimleri Enstitüsü, 2014)
Antimicrobial peptides of the epithelium play a significant role in the innate immune response in the oral cavity, which is constantly exposed to microbes. Type 2 diabetes mellitus (T2DM) is a highly prevalent metabolic ...
Bazı 2-(4-Sübstitüe)Fenil-5-Benziliden P-Sübstitüebenziliden-3-Fenilaminotiyazolidin-4-On Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2014)
In this study, 2 new compunds having 3-
(phenylamino)-2-[4-(1H-1,2,4-triazole/imidazolyl)phenyl]-1,3-thiazolidin-4-one
(Compounds 1,2) and 9 new compounds having 5-(benzylidene/-psubstitutedbenzylidene)-
3-(phenylamin ...
Pantoprazol Metabolizmasında Sitokrom P450 Enzimleri 2C19, 3A4, 3A5 ve İlaç Transporteri MDR1’in Genetik Polimorfizmlerinin Etkileri ve Tedavi Yanıtındaki Önemi
(Tıp Fakültesi, 2013)
Pantoprazole inhibits proton pump which is the last phase of the hydrochloric acid generation in stomach. Pantoprazole is metabolised by cytochrome P450 (CYP) enzymes CYP2C19 and CYP3A4. It is a substrate of the MDR1 ...
Torakotomi sonrası uygulanan transkütan elektriksel sinir stimülasyonunun ağrı üzerine etkisi
(Sağlık Bilimleri Enstitüsü, 2013)
The study has been conducted to investigate the effect of transcutaneous nerve stimulation (TENS) implementation on pain and analgesics consumption of patients undergoing posterolateral thoracotomy as a randomly controlled ...
Yetişkin Türk Popülasyonu Için Yaş Belirlemede Iki Farkli Metodun Uygulanabilirliklerinin Panoramik Görüntülerde Incelenmesi
(Sağlık Bilimleri Enstitüsü, 2015)
Age estimation is a complex and important issue in forensic sciences. Teeth, being one of the toughest and most durable tissues in the living organisms and being able to preserve their morphology longer compared to other ...
Development and Application of Novel Machine Learning Approaches for Rna-Seq Data Classification
(Sağlık Bilimleri Enstitüsü, 2015)
RNA-Seq is a recent and efficient technique that uses the capabilities of next-generation sequencing technology in characterizing and quantifying transcriptomes. This technique has revolutionized the gene-expression profiling ...