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Toplam kayıt 132, listelenen: 51-60
Reactivation of Camp Pathway by Pde4D Inhibition Represents A Novel Druggable Axis for Overcoming Tamoxifen Resistance in Er-Positive Breast Cancer
(Amer Assoc Cancer Research, 2018)
Purpose: Tamoxifen remains an important hormonal therapy for ER-positive breast cancer; however, development of resistance is a major obstacle in clinics. Here, we aimed to identify novel mechanisms of tamoxifen resistance ...
Recurrence Risk and Prognostic Parameters in Stage I Rectal Cancers
(Asian Pacific Organization Cancer Prevention, 2014)
Background: The standard therapy for stage I rectum cancer is surgical resection. Currently, there is no strong evidence to suggest that any type of adjuvant therapy is beneficial. The risks of local relapse and distant ...
Allogeneic Hematopoietic Sct For Adults Aml Using I.V. Bu In The Conditioning Regimen: Outcomes And Risk Factors For The Occurrence Of Hepatic Sinusoidal Obstructive Syndrome
(Nature Publishing Group, 2014)
I.v. BU is frequently used in the conditioning regimen prior to allogeneic hematopoietic SCT (allo-HSCT); however, overall outcomes, incidence of hepatic sinusoidal obstructive syndrome (SOS) and its risk factors are not ...
Characteristics Of Hepatocellular Carcinoma Aggressiveness Factors In Turkish Patients
(Karger, 2018)
A large cohort of hepatocellular carcinoma (HCC) patients from several collaborating Turkish institutions were examined for the tumor parameters of maximum diameter (MTD), portal vein thrombosis (PVT), and alpha-fetoprotein ...
Clinicopathological Characteristics Of Hepatocellular Carcinoma In Turkey
(Asian Pacific Organization Cancer Prevention, 2012)
Background: Hepatocellular carcinoma (HCC), the main malignant tumor of the liver, is very common and highly lethal. The aim of this study was to determine its clinicopathologic characteristics and risk factors in Turkey. ...
Differential Diagnosis Of Basal Cell Carcinoma And Benign Tumors Of Cutaneous Appendages Originating From Hair Follicles By Using Cd34
(Asian Pacific Organization Cancer Prevention, 2010)
Background and Aims: Differential diagnosis of the group of benign trichoblastomas, trichofolliculomas, trichoadenomas and trichoepitheliomas, and basal cell carcinomas (BCCs) is troublesome for the clinician as well as ...
Gemcitabine Combined With The Monoclonal Antibody Nimotuzumab Is An Active First-Line Regimen In Kras Wildtype Patients With Locally Advanced Or Metastatic Pancreatic Cancer: A Multicenter, Randomized Phase Iib Study
(Oxford Univ Press, 2017)
Background: This randomized study was designed to investigate the superiority of gemcitabine (gem) plus nimotuzumab (nimo), an anti-epidermal growth factor receptor monoclonal antibody, compared with gem plus placebo as ...
Nivolumab For Relapsed Or Refractory Hodgkin Lymphoma: Real-Life Experience
(Oxford Univ Press, 2017)
Background: Reed-Sternberg cells of classical Hodgkin's lymphoma (cHL) are characterized by genetic alterations at the 9p24.1 locus, leading to over-expression of programmed death-ligand 1 and 2. In a phase 1b study, ...
Natural History Of T1N0M0 Hepatocellular Carcinoma: Large-Scale Study In The United States
(Karger, 2017)
Background: Hepatocellular carcinoma (HCC) prognosis depends on clinicopathological features in addition to the treatment provided. We aimed to assess the natural history of TNM stage I HCC tumors which received different ...
A Retrospective Multicenter Evaluation of Cutaneous Melanomas in Turkey
(Asian Pacific Organization Cancer Prevention, 2014)
Background: We defined melanoma distribution in a large series of Turkish patients and evaluated the prognostic parameters of melanomas. Materials and Methods: A total of 1574 patients' data was retrospectively collected ...