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Toplam kayıt 43, listelenen: 11-20
Short-Term and Long-Term Fk506 Treatment Alters the Vascular Reactivity of Renal and Mesenteric Vascular Beds
(Japanese Pharmacological Soc, 2006)
The aims of this study were to investigate the role of endothelin-1 in FK506-induced hypertension and vascular dysfunction of rats treated with the drug for 8 (short-term) or 30 (long-term) days and to measure malondialdehyde ...
Sedative Effect of Centranthus Longiflorus Ssp Longiflorus in Rats and the Influence of Adrenalectomy on Its Effect
(Pharmaceutical Soc Japan, 2007)
Sedative effect of the aqueous extract of Centranthus longiflorus ssp. longiflorus (Cle-1) on intact and adrenalectomized rats was investigated using a thiopental sleeping test to clarify the relationship of this effect ...
A Double-Blind, Placebo Controlled, Cross-Over Trial of Adjunctive Donepezil For Cognitive Impairment In Schizophrenia
(Oxford Univ Press, 2004)
Although there have been several case reports suggesting the beneficial effect of acetylcholinesterase inhibitors in the cognitive deficits seen in schizophrenia, controlled studies have revealed contradictory results. The ...
Development And In Vitro Evaluation Of Pantoprazole-Loaded Microspheres
(Informa Healthcare, 2008)
Pantoprazole is a proton pump inhibitor prodrug used in the treatment of gastric ulcers and gastroesophageal disease. Pantoprazole must be absorbed in the gastrointestinal tract and because it is unstable under acidic ...
Effects Of Rosiglitazone Treatment On The Pentose Phosphate Pathway And Glutathione-Dependent Enzymes In Liver And Kidney Of Rats Fed A High-Fat Diet
(Elsevier Science Inc, 2004)
Background: Animals fed high-fat diets have been shown to develop hyperglycemia, insulin resistance, hyperlipidemia, and moderate obesity, which resemble the human metabolic syndrome. Obesity, the metabolic syndrome, and ...
Effects Of Cadmium And Zinc Ions On Purified Lamb Kidney Cortex Glucose-6-Phosphate Dehydrogenase Activity
(Taylor & Francis Ltd, 2006)
Glucose-6-phosphate dehydrogenase (G-6-PD) is the first enzyme in the pentose phosphate pathway. Cadmium is a toxic heavy metal that inhibits several enzymes. Zinc is an essential metal but overdoses of zinc have toxic ...
Evaluation Of Biological Activity Of Turkish Plants. Rapid Screening For The Antimicrobial, Antioxidant, And Acetylcholinesterase Inhibitory Potential By Tlc Bioautographic Methods
(Swets Zeitlinger Publishers, 2004)
Using thin-layer chromatography (TLC) bioautography, a total of 58 extracts from various organs (aerial parts, leaves, flowers, fruits, roots) of 16 Turkish plants were tested for their antibacterial, antifungal, ...
The Operational Multiple Dosing Half-Life: A Key To Defining Drug Accumulation In Patients And To Designing Extended Release Dosage Forms
(Springer/Plenum Publishers, 2008)
Half-life (t (1/2)) is the oldest but least well understood pharmacokinetic parameter, because most definitions are related to hypothetical 1-compartment body models that don't describe most drugs in humans. Alternatively, ...
Thrombus Localization By Using Streptokinase Containing Vesicular Systems
(Taylor & Francis Ltd, 2006)
Our research focused on the preparation of vesicular drug delivery systems, such as liposomes, noisomes, and sphingosomes, for achieving slow release of entrapped proteins in the circulation to increase half-life, to mask ...
Development Of A Peptide-Containing Chewing Gum As A Sustained Release Antiplaque Antimicrobial Delivery System
(Springer, 2007)
The objective of this study was to characterize the stability of KSL-W, an antimicrobial decapeptide shown to inhibit the growth of oral bacterial strains associated with caries development and plaque formation, and its ...