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Toplam kayıt 640, listelenen: 1-10
Akut Omurilik Travmalarında Kullanılmak Üzere Nöroprotektif İlaç Yüklü Nanopartiküler İlaç Taşıyıcı Sistem Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)
Methyl prednisolone sodium succinate (MPSS) is a
very hydrophilic synthetic glucocorticoid. Although it is usually used for its antiinflammatory
effects, it is still the only efficacy proven therapeutic agent which is ...
Kimyasal Olarak İndüklenmiş Meme Kanseri Modelinde Klorofilin-Cu Kompleksinin Antioksidan Etkinliğinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2015)
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Investigation show that glutathione and related enzymes are often overexpressed in tumor cells ...
Farmasötik Preparatlardan ve Gıdalardan Tobramisin Tayini İçin Moleküler Baskılanmış Nanosensörlerin Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2013)
In this thesis study, the molecularly imprinted glassy carbon and quartz crystal microbalance (QCM) nanosensors were developed for the determination of tobramycin. For QCM nanosensor, firstly the modification of gold surface ...
Karaciğer ve Meme Kanseri Hücreleri ile Embriyonik Böbrek Hücrelerinde Doksorubisinin Apoptotik Genlerin ve Mdr-1 Geninin Ekspresyon Düzeylerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2013)
In this study, in order to investigate roles of certain genes and expression levels of these genes in apoptosis, MCF-7 (breast), HEPG2 (liver) cancer cells and HEK293 embryonic kidney cells were treated with increasing ...
İnsan Serum Bütirilkolinesterazı ve Eritrosit Asetilkolinesterazının Statin Türevleri ile Etkileşiminin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2014)
To investigate effects of statins on cholinesterases, Butyrylcholinesterase (BChE; E.C.3.1.1.8 ) was purified from human plasma through acid dialysis, DEAE-Tris Acryl M ion exchange and Procainamide-Sepharose 4B chromatography ...
Development and Validation of an Ultra-Performance Liquid Chromatographic-Tandem Mass Spectrometry (Uplc-Ms/Ms) Method for Determination of Betamethasone or Dexamethasone in Pharmaceutical Preparations
(Sağlık Bilimleri Enstitüsü, 2013)
Development and Validation of an Ultra-Performance Liquid Chromatographic-Tandem Mass Spectrometry (UPLC-MS/MS) Method for Determination of Betamethasone or Dexamethasone in Pharmaceutical Preparations, Hacettepe University, ...
Metastatik Meme Kanseri Hücrelerinde Mtor Üzerine Etkili Bazı Mekanizmaların Araştırılması
(Sağlık Bilimleri Enstitüsü, 2013)
Signal trunsduction pathways play crucial roles in breast cancer pathogenesis. mTOR, which plays a central role in cell proliferation and interacts with several cell components, is selected as a target in MDA-MB- 231 ...
Serotoninin Renal Hasardaki Rolü
(Sağlık Bilimleri Enstitüsü, 2015)
In various acute and chronic renal diseases, tissue damage occurs and platelet
activation is observed. Recent studies suggest that some factors released from
activated platelets may participate in inflammation and fibrosis ...
Dinitroanilin Herbisitlerin Neden Olduğu Genotoksik Etkilerin ve Epigenetik Değişikliklerin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)
It has been shown that genetic damage has an improtant role in the mechanisms of cancer and other chronic diseases that have been observed all over the world. Recently, theory about that epigenetic changes are also responsible ...
Üveit Patolojisinde Pteridin ve Kinürenin Yolaklarındaki Olası Değişimlerin Incelenmesi
(Sağlık Bilimleri Enstitüsü, 2014)
Uveitis is an intraocular inflammation affecting the highly vascularised uveal tissue. Early recognition and appropriate therapeutic intervention of uveitis is important since it may be associated with systemic disease and ...