Acil Servise Özkıyım Amaçlı Ilaç Alma Şikayetiyle Başvuran Hastalarda Görülen Elektrolit Bozuklukları

Abstract

Intoxication cases are considered one of the most important causes of morbidity and mortality among the patients addmitting to emergency departments. Evaluation of blood electrolyte levels is recommended in drug specific treatment guidelines in intoxicaiton cases. In this study the files of patients above 18 years old who were diagnosed drug intoxication in Hacettepe University Faculty of Medicine Adult Emergency Department. between 1st January 2005 and 1st February 2013 were retrospectively evaluated. Demographic profiles and blood test results of the patients were recorded. There were 323 patients and the median age was 27 (18-72) years. Sixty seven (20.7%) patients were male and 256 (79.2%) were female. While the most admission month was April, the least was February. It has been detected that 77.1% of patients have taken more than the daily recommended dose. As we compare the drugs: nonsteroidal anti-inflammatory drugs (NSAID’s) were the first with 21.1%; paracetamols were second with 20.5%; selective serotonin reuptake inhibitors were third with 17.7% and tricyclic antidepressants were fourth with 15.5% ratio. The relations between toxic dose intake of these drugs and blood sodium, potassium, BUN, creatine, AST, ALT, INR, cardiac markers and blood gase analyses were investigated. Only relation between serum sodium levels and intake of toxic dose of NSAID’s have been found statistically significant. As a result of this study we suggest that blood testing in high dose of intoxication cases must be planned specific to the drug.