In this study, feasibility of Magnetic Resonance Imaging (MRI) based treatment planning system instead of computed tomography (CT) in SRC and SBRT was evaluated. Three different scenarios were created for density and ...

Continuous activation of HER2 leads to the deregulation of various biological responses such as cell proliferation, survival, and migration, and tumor growth. eEF2K is a protein kinase involved in the regulation of protein ...

The purpose of Total Body Irradiation (TBI) in radiotherapy is to suppress the immune system of the patient by destroying bone marrow cells, prepare the host for bone marrow transplantation and enhance the antitumor effect. ...

Inhibition of tumor angiogenesis has been extensively utilized in the treatment of metastatic colorectal cancer and renal cell carcinoma. Complete disruption of tumor angiogenesis results in hypoxia which promotes tumor ...

Uzun, S, Investigation of The Role of β-catenin N-terminal Domain Alterations in Neoplastic Processes, Hacettepe University Graduate School of Health Sciences Tumor Biology and Immunology Program Doctor of Philosophy ...

Lung cancer has the highest mortality rate in both men and women worldwide. With our developing technology and knowledge, the research of methods in cancer targeted treatments have turned to target such as tumor microenvironment, ...

The tumor microenvironment (TME) contains cancer-associated fibroblasts (CAFs) and their tumor-supportive role helps to build an environment in favor of cancer cell progression. Recent researches have revealed that targeting ...