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Fare Miyoblast Hücre Hattında KLF5 Geninin Farklılaşma Sürecine Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2014)
Embryonic development of the skeletal muscle and injury repair share several molecular events such as the myogenic regulatory factors (MRFs) and paired-homeobox transcription factors. Myogenesis is a highly regulated complex ...
Demir Birikimine Bağlı Yetmezlik Gelişen Endokrin Organların T2 Ve T2* Değerlerinin Belirlenmesi
(Tıp Fakültesi, 2013)
The purpose of this study at first stage is to determine the normal R2/T2 for thyroid and pituitary gland, and R2*/T2* values for pancreas, and then at the second stage to evaluate if there is any difference between tl ...
Çocukluk Dönemi Steroide Dirençli Nefrotik Sendroma Sebep Olan Yeni Genlerin Bulunması
(Sağlık Bilimleri Enstitüsü, 2012)
Steroid resistant nephrotic syndrome (SRNS), despite being a rare disease, is the second most common cause of end stage kidney failure in childhood and early adulthood. However the heterogeneity and rarity (<1%) of disease ...
Pantoprazol Metabolizmasında Sitokrom P450 Enzimleri 2C19, 3A4, 3A5 ve İlaç Transporteri MDR1’in Genetik Polimorfizmlerinin Etkileri ve Tedavi Yanıtındaki Önemi
(Tıp Fakültesi, 2013)
Pantoprazole inhibits proton pump which is the last phase of the hydrochloric acid generation in stomach. Pantoprazole is metabolised by cytochrome P450 (CYP) enzymes CYP2C19 and CYP3A4. It is a substrate of the MDR1 ...
Development and Application of Novel Machine Learning Approaches for Rna-Seq Data Classification
(Sağlık Bilimleri Enstitüsü, 2015)
RNA-Seq is a recent and efficient technique that uses the capabilities of next-generation sequencing technology in characterizing and quantifying transcriptomes. This technique has revolutionized the gene-expression profiling ...
Nazofarinks Kanserli Hastalarda Radyoterapi Sonrası MRG'de Klivustaki Medüller Intensite Değişiklikleri
(Tıp Fakültesi, 2014)
Clivus is commonly involved in nasopharyngeal carcinoma (NPC) and the intensity changes in the bone marrow can persist after the radiation therapy (RT) even after the disappearance of the mucosal soft tissue mass. Furthermore ...
Dual-Enerji Bt Kolonografi: Kolorektal Tümörlerin Dual Enerji BT Özellikleri
(Tıp Fakültesi, 2013)
We aimed to define the dual-energy CT characteristics of colorectal cancers and stool. Fifty consecutive patients were included who was referred for staging CT of a colorectal tumor between June 2011 and November 2012. ...
Lone Paroksizmal Atriyal Fibrilasyonu Olan Hastalarda Endotel Fonksiyonları, İntra-Interatriyal İleti Özellikleri ve Diyastolik Fonksiyonlar Arasındaki İlişkinin Değerlendirilmesi
(Tıp Fakültesi, 2012)
Risk factors such as endothelial dysfunction, diastolic dysfunction and non-homogeneous atrial conduction, alone or in association with each other may lead to atrial remodelling and play a role in development and maintenance ...
Tip 2 Diyabetik Hastalarda Serumda Gelişmiş Glikasyon Ürünlerin Çözünür Reseptörü (Srage) Seviyesiyle Sol Ventrikül Diyastolik Disfonksiyonun İlişkisi
(Tıp Fakültesi, 2013)
The binding of advanced glycation end products (AGEs) to their receptor (RAGE) plays an important role in the development of diabetic cardiovascular complications. RAGE has a circulatingsecretory receptor form soluble RAGE ...
Polikistik Over Sendromu Tanılı Hastalarla, Polikistik Over Sendromu Tanısı Olmayan Sağlıklı Kadınların Beyin Manyetik Rezonans Görüntülerinin Karşılaştırılması, Vücut Kitle Indeksi ve Hormon Düzeyleri ile Ilişkilerinin Belirlenmesi
(Tıp Fakültesi, 2015)
Polycystic ovary syndrome (PCOS) is a common and complex metabolic and endocrine disorder which is characterized by hyperandrogenism, chronic anovulation and polycystic ovaries on ultrasound. Obesity is another common ...
