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Quality of Life and Related Factors Among Chronic Hepatitis B-Infected Patients: A Multi-Center Study, Turkey

dc.contributor.authorKaracaer, Zehra
dc.contributor.authorCakir, Banu
dc.contributor.authorErdem, Hakan
dc.contributor.authorUgurlu, Kenan
dc.contributor.authorDurmus, Gul
dc.contributor.authorInce, Nevin Koc
dc.contributor.authorOzturk, Cinar
dc.contributor.authorHasbun, Rodrigo
dc.contributor.authorBatirel, Ayse
dc.contributor.authorYilmaz, Esmeray Mutlu
dc.contributor.authorBozkurt, Ilkay
dc.contributor.authorSunbul, Mustafa
dc.contributor.authorAynioglu, Aynur
dc.contributor.authorAtilla, Aynur
dc.contributor.authorErbay, Ayse
dc.contributor.authorInci, Ayse
dc.contributor.authorKader, Cigdem
dc.contributor.authorTigen, Elif Tukenmez
dc.contributor.authorKaraahmetoglu, Gokhan
dc.contributor.authorCoskuner, Seher Ayten
dc.contributor.authorDik, Ebru
dc.contributor.authorTarakci, Huseyin
dc.contributor.authorTosun, Selma
dc.contributor.authorKorkmaz, Fatime
dc.contributor.authorKolgelier, Servet
dc.contributor.authorKaradag, Fatma Yilmaz
dc.contributor.authorErol, Serpil
dc.contributor.authorTurker, Kamuran
dc.contributor.authorNecan, Ceyda
dc.contributor.authorSahin, Ahmet Melih
dc.contributor.authorErgen, Pinar
dc.contributor.authorIskender, Gulsen
dc.contributor.authorKorkmaz, Pinar
dc.contributor.authorEroglu, Esma Gulesen
dc.contributor.authorDurdu, Yasemin
dc.contributor.authorUlug, Mehmet
dc.contributor.authorDeniz, Suna Secil
dc.contributor.authorKoc, Filiz
dc.contributor.authorAlpat, Saygın Nayman
dc.contributor.authorOztoprak, Nefise
dc.contributor.authorEvirgen, Omer
dc.contributor.authorSozen, Hamdi
dc.contributor.authorDogan, Mustafa
dc.contributor.authorKaya, Selcuk
dc.contributor.authorKaya, Safak
dc.contributor.authorAltindis, Mustafa
dc.contributor.authorAslan, Emel
dc.contributor.authorTekin, Recep
dc.contributor.authorSezer, Busra Ergut
dc.contributor.authorOzdemir, Kevser
dc.contributor.authorErsoz, Gulden
dc.contributor.authorSahin, Ahmet
dc.contributor.authorCelik, Ilhami
dc.contributor.authorAydin, Emsal
dc.contributor.authorBastug, Aliye
dc.contributor.authorHarman, Rezan
dc.contributor.authorOzkaya, Hacer Deniz
dc.contributor.authorParlak, Emine
dc.contributor.authorYavuz, Ilknur
dc.contributor.authorSacar, Suzan
dc.contributor.authorComoglu, Senol
dc.contributor.authorYenilmez, Ercan
dc.contributor.authorSirmatel, Fatma
dc.contributor.authorBalkan, Ilker Inanc
dc.contributor.authorAlpay, Yesim
dc.contributor.authorHatipoglu, Mustafa
dc.contributor.authorDenk, Affan
dc.contributor.authorSenol, Gunes
dc.contributor.authorBitirgen, Mehmet
dc.contributor.authorGeyik, Mehmet Faruk
dc.contributor.authorGuner, Rahmet
dc.contributor.authorKadanali, Ayten
dc.contributor.authorKarakas, Ahmet
dc.contributor.authorNamiduru, Mustafa
dc.contributor.authorUdurgucu, Hatice
dc.contributor.authorBoluktas, Rukiye Pinar
dc.contributor.authorKaragoz, Ergenekon
dc.contributor.authorOrmeci, Necati
dc.date.accessioned2019-12-10T10:57:01Z
dc.date.available2019-12-10T10:57:01Z
dc.date.issued2016
dc.identifier.issn1477-7525
dc.identifier.urihttps://doi.org/10.1186/s12955-016-0557-9
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095975/
dc.identifier.urihttp://hdl.handle.net/11655/14763
dc.description.abstractBackground The aim of this study was to assess health-related quality of life (HRQOL) among chronic hepatitis B (CHB) patients in Turkey and to study related factors. Methods This multicenter study was carried out between January 01 and April 15, 2015 in Turkey in 57 centers. Adults were enrolled and studied in three groups. Group 1: Inactive HBsAg carriers, Group 2: CHB patients receiving antiviral therapy, Group 3: CHB patients who were neither receiving antiviral therapy nor were inactive HBsAg carriers. Study data was collected by face-to-face interviews using a standardized questionnaire, Short Form-36 (SF-36) and Hepatitis B Quality of Life (HBQOL). Values equivalent to p < 0.05 in analyses were accepted as statistically significant. Results Four thousand two hundred fifty-seven patients with CHB were included in the study. Two thousand five hundred fifty-nine (60.1 %) of the patients were males. Groups 1, 2 and 3, consisted of 1529 (35.9 %), 1721 (40.4 %) and 1007 (23.7 %) patients, respectively. The highest value of HRQOL was found in inactive HBsAg carriers. We found that total HBQOL score increased when antiviral treatment was used. However, HRQOL of CHB patients varied according to their socio-demographic properties. Regarding total HBQOL score, a higher significant level of HRQOL was determined in inactive HBV patients when matched controls with the associated factors were provided. Conclusions The HRQOL score of CHB patients was higher than expected and it can be worsen when the disease becomes active. Use of an antiviral therapy can contribute to increasing HRQOL of patients.
dc.relation.isversionof10.1186/s12955-016-0557-9
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleQuality of Life and Related Factors Among Chronic Hepatitis B-Infected Patients: A Multi-Center Study, Turkey
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalHealth and Quality of Life Outcomes
dc.contributor.departmentHalk Sağlığı
dc.identifier.volume14
dc.description.indexPubMed
dc.description.indexWoS
dc.description.indexScopus


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