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dc.contributor.authorErbil, Bulent
dc.contributor.authorErsoy, Gurkan
dc.contributor.authorOzkutuk, Aydan
dc.contributor.authorAkarca, Funda Karbek
dc.contributor.authorKorkmaz, Tanzer
dc.contributor.authorDemir, Omer Faruk
dc.contributor.authorKiyan, Selahattin
dc.date.accessioned2019-12-10T10:37:17Z
dc.date.available2019-12-10T10:37:17Z
dc.date.issued2014
dc.identifier.issn1306-696X
dc.identifier.urihttps://doi.org/10.5505/tjtes.2014.63993
dc.identifier.urihttp://hdl.handle.net/11655/13998
dc.description.abstractBACKGROUND: The objective of this study is to examine the effectiveness of oral antibiotics in the prevention of infection development in traumatic wounds. METHODS: Forty Wistar albino rats were divided into five groups of eight animals. After the crushed wound model was made on the back of the rats, wounds were closed with a simple suture and Staphylococcus aureus ATCC 29213 strain was used to create infection. All rats apart from the controls were given oral gavage with antibiotics, including cephalexin, amoxicillin-clavulanate, clarithromycin (CAM), or levofloxacin for 5 days. Wounds were evaluated qualitatively and quantitatively on 5th day approximately 18 h after the last treatment. RESULTS: In the quantitative evaluation, no infection was observed in the treatment groups with amoxicillin-clavulanate, CAM, cephalexin, or levofloxacin. There was no significant difference on the numbers of bacteria found in the wounds among the groups. In terms of quantitative inflammation findings, no hyperemia or pus was detected in the groups that were given medication. Furthermore, no statistically significant difference was found among the groups in terms of induration. CONCLUSION: Oral prophylactic antibiotics have been found to be effective in the prevention of wound infection in the traumatic crushed wound model infected with S. aureus in rats.
dc.language.isoen
dc.publisherTurkish Assoc Trauma Emergency Surgery
dc.relation.isversionof10.5505/tjtes.2014.63993
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectEmergency Medicine
dc.titleThe Effects of Oral Antibiotics on Infection Prophylaxis in Traumatic Wounds
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalUlusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal Of Trauma & Emergency Surgery
dc.contributor.departmentAcil Tıp
dc.identifier.volume20
dc.identifier.issue4
dc.identifier.startpage231
dc.identifier.endpage235
dc.description.indexWoS


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