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Isolation And Structure Elucidation Of Uncommon Secondary Metabolites From Cistus Salviifolius L.
(Acg Publications, 2015)
To our knowledge this is the first report on the isolation of a flavonoid glycoside: quercetin 3-O-alpha-arabinopyranoside (5), two phenylbutanon glycosides: 4-(4'-O-[6''-O-galloyl-beta-galactopyranosyl]-3'-hydroxyphenyl ...
Microwave-Assisted Synthesis Of Condensed 1,4-Dihydropyridines As Potential Calcium Channel Modulators
(Scientific Technical Research Council Turkey-Tubitak, 2015)
This study reports the design, synthesis, and calcium channel modulatory activity evaluation of a series of 14 novel fused 1,4-dihydropyridine derivatives. The molecular design of the compounds was based on modifications ...
Synthesis and Molecular Modeling Studies of Naproxen-Based Acyl Hydrazone Derivatives
(Scientific Technical Research Council Turkey-Tubitak, 2015)
A series of N-acylhydrazone derivatives (2a-2p) containing 6-methoxy-naphthalene and acylhydrazone moieties were synthesized in good yield using microwave irradiation and developed as potential COX-2 inhibitors. Furthermore, ...
Evaluation Of A Capillary Electrophoresis Method For Routine Determination Of Varenicline Tartrate In Quality-Control Laboratories
(Soc Chemists Technologists Madeconia, 2015)
In this study, analyses were carried out on a fused-silica capillary (i.d. 50.0 mu m, total length 48.5 cm, and effective length 40.0 cm) in normal mode by applying a voltage of 20 kV. Sample injections were made in ...
Few Drugs Display Flip-Flop Pharmacokinetics And These Are Primarily Associated With Classes 3 And 4 Of The Bddcs
(Wiley, 2015)
This study was conducted to determine the number of drugs exhibiting flip-flop pharmacokinetics following oral (p.o.) dosing from immediate-release dosage forms and if they exhibit a common characteristic that may be ...
Preparation and Physicochemical Characterizations of Solid Lipid Nanoparticles Containing Dotap for Dna Delivery
(Scientific Technical Research Council Turkey-Tubitak, 2015)
The aim of this study was to prepare and evaluate stable cationic solid lipid nanoparticles (SLNs) as colloidal carriers for gene therapy. SLNs were mainly composed of three different biocompatible and biodegradable matrix ...
The High Pressure Structure And Equation Of State Of 2,6-Diamino-3,5-Dinitropyrazine-1-Oxide (Llm-105) Up To 20 Gpa: X-Ray Diffraction Measurements And First Principles Molecular Dynamics Simulations
(Amer Inst Physics, 2015)
Recent theoretical studies of 2,6-diamino-3,5-dinitropyrazine-1-oxide (C4H4N6O5 Lawrence Liver-more Molecule No. 105, LLM-105) report unreacted high pressure equations of state that include several structural phase ...
Self-Assembled Peptide Amphiphile Nanofibers And Peg Composite Hydrogels As Tunable Ecm Mimetic Microenvironment
(Amer Chemical Soc, 2015)
Natural extracellular matrix (ECM) consists of complex signals interacting with each other to organize cellular behavior and responses. This sophisticated microenvironment can be mimicked by advanced materials presenting ...
Boric Acid: A Simple Molecule of Physiologic, Therapeutic and Prebiotic Significance
(Walter De Gruyter Gmbh, 2015)
Boric acid, H3BO3, is a weak acid and at physiological pH is in the form of an uncharged small molecule. Behaving as a Lewis acid, it forms complexes with amino-and hydroxy acids, carbohydrates, nucleotides and vitamins ...
Effect of Sonic Treatment on The Permeation Performance of Cellulose Acetate Membranes Modified By N-Sio2
(Scientific Technical Research Council Turkey-Tubitak, 2015)
Cellulose acetate (CA) membranes were modified by nano-silicon dioxide (n-SiO2), and they were exposed to ultrasonic waves at a frequency of 35 kHz. The effect of sonication on their water sorption tendency and permeation ...