Atık Sulardan Estradiol Uzaklaştırılması İçin E2 Baskılanmış Nanopartikül Bakteriyel Selüloz Kompozit Sistemin Hazırlanması

Abstract

Many environmental disruptors from various sources act as Endocrine Disrupting Chemicals and have adverse effects on natural life and on human by effecting endocrine system functions. Individual effects may lead to social problems. In natural life, effects of endocrine disruptors appear as reproductive system and developmental anomalies. It was reported that plasma vitellogenin level in fish living near wastewater treatment plants in the United Kingdom increases due to steroids, oestrogen and alkylphenols in streams and thus feminization in male fish occurs. Natural hormone 17β-oestradiol and contraceptive 17α-ethinylestradiol are the most potent oestrogens and small concentrations in wastewater treatment plants has advers effects on fish reproduction. E2 is a natural hormone effecting the improvement and progression of sexual characteristics, and also the maturation and function of sexual organs. Also found in male in small amounts. E2 is also associated with neuroendocrine system and bone structure and may promote cancer in target organs. Like all steroids, E2 has the same cyclopentan-o- perhydrophenanthrene ring as main component cholesterol. Main ring structure consists of three hexagonal and a pentagonal rings. Like other steroids, 8 E2 is also characterized with phenolic ring. It has also a hydroxyl group in β position of C17 carbon. In this thesis, removal of trace amounts of 17β-oestradiol from wastewaters by molecular imprinting technique is aimed.