Browsing Eczacılık Meslek Bilimleri Bölümü by Funding "Yok"
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1-FENİL-2-(1H-İMİDAZOL-1-İL)ETANON OKSİM ESTERLERİNİN SENTEZİ VE BİYOLOJİK ETKİLERİ ÜZERİNDE ÇALIŞMALAR
(Sağlık Bilimleri Enstitüsü, 2020-02-19)Yurtoglu, S., Studies on Synthesis and Biological Effects of 1-Phenyl-2-(1H-imidazol-1-yl) ethanone oxime esters , Hacettepe University, Institute of Health Sciences, MS Thesis in Pharmaceutical Chemistry, Ankara, 2020. ... -
Akrilamid ve 5-Hidroksimetilfurfural'in Olası Genotoksik Etkilerinin Tek Hücre Jel Elektroforez Yöntemi ile İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)The cooking processes of foods containing carbohydrates forms acrylamide and 5-hydroxymethylfurfural (HMF) as a result of Maillard reaction. According to previous in vivo and in vitro tests, these two substances ... -
Alkol Esteri Yapısındaki Yeni Azol Türevlerinin Sentezi, Biyolojik Aktiviteleri, Moleküler Modelleme Çalışmaları ve Yapı-Etki İlişkileri
(Sağlık Bilimleri Enstitüsü, 2023)In this study, various carboxylic acid esters of 1-aryl-2-(1H-imidazol-1-yl/1H-1,2,4-triazol-1-yl)ethanol was synthesized in order to discovery new organic compounds with antimicrobial and anticholinesterase effects; ... -
Antimikobakteriyel Aktivite Göstermesi Beklenen Bazı 2,3-Disübstitüe-5-Metil-4-Tiyazolidinon Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2019-09-07)Ekinci, A. S., Studies on Some 2,3-Disubstituted-5-Methyl-4-Thiazolidinone Derivatives Expected to Show Antimycobacterial Activity, Hacettepe University Graduate School of Health Sciences, MS Thesis in Pharmaceutical ... -
ANTİMİKROBİYAL TEDAVİDE İNTRAVENÖZDEN ORALE GEÇİŞ PROTOKOLÜ GELİŞTİRİLMESİ VE UYGULAMASININ GEÇİŞE ETKİSİ VE KLİNİK ECZACININ ROLÜ
(Sağlık Bilimleri Enstitüsü, 2024)In antimicrobial treatment, it is recommended to switch from intravenous to oral therapy in eligible patients to reduce complications and ensure pharmacoeconomic treatment. In this study, we evaluated the effect of a ... -
Assessment Of Genotoxic Effects Of Pendimethalin In Chinese Hamster Over Cells By The Single Cell Gel Electrophoresis (Comet) Assay
(Turkish Pharmacists Association, 2017)Objectives: Pendimethalin (N-(1-ethylpropyl)-3,4-dimethyl-2,6-dinitrobenzeneamine) is a dinitroaniline herbicide compound which selectively controls weeds. It is a cell division and growth inhibitor. It descends plants in ... -
Azol Halkası Taşıyan COX İnhibitörlerinin Sentezi ve Antimikrobiyal Aktivitelerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2024-01)Nonsteroidal anti-inflammatory drugs (NSAIDs) are the group of drugs that show their effects by inhibiting cyclooxygenase (COX) enzymes and are frequently used in the treatment of pain and inflammation. In addition to these ... -
Bazı 2-Sübstitüe-4-(Furan-2-İlmetil)-6-MetilPiridazin-3(2H)-on Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2021-07-08)In this study, 16 new compounds, 2-[5-(furan-2-ylmethyl)-3-methyl-6-oxopyridazin-1(6H)-yl]-N-(aryl)acetamide (5a-j) and 4-(furan-2-ylmethyl)-6-methyl-2-[2-oxo-2-(4-arylpiperazin-1-yl)ethyl]pyridazin-3(2H)-one (6a-f), which ... -
Benzoksazolinon-hidrazon farmakoforu taşıyan dual etkili mao-aromataz inhibitörlerinin tasarımı ve sentezi: in siliko ve in vitro çalışmalar
(Sağlık Bilimleri Enstitüsü, 2022)Taşçi, N., Design and synthesis of dual MAO-Aromatase inhibitors containing benzoxazolinone-hydrazone pharmacophore: In silico and in vitro studies, Hacettepe University, Graduate School of Health Sciences PhD Thesis in ... -
Çocuklar ve ebeveynleri için kullanılacak ‘ilaç tedavisine uyunç’ ve ‘ilaca ilişkin hasta/hasta yakını yaklaşımı’ ölçeklerinin geliştirilmesi ve değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)It is known that the prescription rate of psychotropic drugs in adolescents is increasing, and medication adherence is lower in children and adolescents compared to adults. The effectiveness of psychotropic drugs is very ... -
Dibutil Ftalatın İnsan Akciğer Hücre Hattına Toksik Etkilerinin Değerlendirilmesi ve Askorbik Asit ve N-Asetilsisteinin Olası Koruyucu Etkileri
(Sağlık Bilimleri Enstitüsü, 2020)Endocrine disruptings are chemical substances which are generally produced by humans that disrupt the normal functioning of the body by imitating or blocking hormones. The mostly studied phthalate derivative is ... -
Dihidropiridin Türevlerinin Sentezi ve L-/T-Tipi Kalsiyum Kanal Bloke Edici Aktiviteleri
(Sağlık Bilimleri Enstitüsü, 2022-07-19)1,4- Dihydropyridines (DHPs) are the most well known inhibitors of L-type calcium channels and have important therapeutic value against cardiovascular diseases. Since they target different calcium channel subtypes, they ... -
Elazığ Bölgesi Siyah Üzümünün (Vitis Vinifera L.) Endüstriyel Atıklarından Yüksek Saflıkta Resveratrol Elde Edilmesi
(Sağlık Bilimleri Enstitüsü, 2024)Akcan, A.Y., Obtaining High Purity Resveratrol from Industrial Wastes of Black Grapes (Vitis Vinifera L.), Hacettepe University, Graduate School of Health Sciences, Pharmacognosy Program, Master of Science Thesis, Ankara, ... -
Evaluation of Oxidative and Antioxidative Parameters in Pediatric Hematopoietic SCT Patients
(Springer Nature, 2012)Conditioning regimens preceding hematopoietic SCT (HSCT) usually consist of high-dose chemotherapy. Chemotherapy and radiation therapy are associated with increased formation of free radicals and depletion of critical ... -
Farelerde lipopolisakkarit ile indüklenen solunum yolu inflamasyonunda mitokondriye hedeflendirilmiş yavaş hidrojen sülfür salıveren AP39'un ve nitrik oksit sentaz inhibitörü asimetrik dimetil arjinin (ADMA)'nın etkilerinin araştırılması
(Sağlık Bilimleri Enstitüsü, 2019)In this study, the effects of mitochondria-targeted slow H2S releasing donor AP39 on lipopolysaccharide (LPS)-induced airway inflammation were investigated in in vitro and in vivo models. In in vitro model tracheal rings ... -
Gentiana olivieri Griseb.’in Nöroprotektif Etkisi
(Sağlık Bilimleri Enstitüsü, 2024-06-25)The genus Gentiana has 400 species in the world and 12 species in Türkiye, and plants belonging to this genus have had a wide range of uses in folk medicine for many years. Gentiana olivieri Griseb. used in Southeastern ... -
In Silico Toksikoloji Yöntemleri ve Uygulamaları Üzerine Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2024)The use of computer-assisted toxicology methods (in silico toxicology, computer-based toxicology etc.) in predicting preclinical toxicological endpoints, clinical side effects, and the metabolism of pharmaceutical ... -
Inula Fragılıs Boıss. & Hausskn. Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2023)Uzun, K., Pharmacognosical studies on Inula fragilis Boiss. & Hausskn., Hacettepe University, Graduate School of Health Sciences, Pharmacognosy Program, PhD Thesis, Ankara, 2023. Inula L. (Asteraceae) species are rich in ... -
İnsan Kolostrum Sütünde Neopterin ve Kinürenin Düzeylerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)Deliveli, S., Examining the amounts of neopterin and kynurenine in human colostrum milk, Hacettepe University Graduate School of Health Sciences, Pharmaceutical Toxicology Program, Master Thesis, Ankara, 2021. Colostrum ... -
Kanser Hastalarında Erişkin Aşılamada Tutum ve Davranışlar Üzerine Etki Eden Faktörlerin Belirlenmesi ve Eczacı Tarafından Verilen Aşı Eğitiminin Etkisinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2022)Intended vaccination rates with the pneumococcal vaccine in cancer patients have not been reached worldwide. This study was aimed to evaluate the impact of clinical pharmacist-provided education on pneumonia and pneumococcal ...
