Browsing Temel Eczacılık Bilimleri Bölümü Makale Koleksiyonu by Issue Date
Now showing items 1-20 of 123
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Cytoskeleton, Microtubules, Tubulin And Colchicine - A Review
(Univ Tokyo Cytologia, 1987) -
Proguanil Metabolism in Relation To S-Mephenytoin Oxidation in A Turkish Population
(Blackwell Science Ltd, 1996)The oxidation of proguanil was studied in 89 unrelated healthy Turkish volunteers after administration of proguanil (single dose, 200 mg, orally). Based on the distribution of the ratio of proguanil to cycloguanil excreted ... -
An Artificial Intelligent Diagnostic System on Differential Recognition of Hematopoietic Cells From Microscopic Images
(Wiley-Liss, 1997)Despite their advantages, none of the automated white blood cell differential counters have replaced the conventional microscopic evaluations of blood and bone marrow slides by hematologists, We have analyzed the smears ... -
The Trypsin-Inhibitory Efficiency Of Human Alpha(2)-Macroglobulin In The Presence Of Alpha(1)-Proteinase Inhibitor: Evidence For The Formation Of An Alpha(2)-Macroglobulin-Alpha(1)-Proteinase Inhibitor Complex
(Harwood Acad Publ Gmbh, Taylor & Francis Group, 1999)The inhibition of bovine pancreatic trypsin was studied at pH 7, 25 degrees C, using mixtures of purified human alpha(2)-macroglobulin (alpha(2)M) and alpha(1)-proteinase inhibitor (alpha(1)PI). The partitioning of the ... -
Morphologic And Mechanical Characteristics Of Engineered Bovine Arteries
(Mosby-Elsevier, 2001)Objective: The ideal small-caliber arterial graft remains elusive despite several decades of intense research. A novel approach to the development of small-caliber arterial prostheses with a biomimetic system for in vitro ... -
A New Species of Acantholimon Boiss. (Plumbaginaceae) from Ankara, Turkey
(Wiley-Blackwell, 2002)Acantholimon anatolicum Dogan & Akaydin sp. nov. (Plumbaginaceae) is described and illustrated. The species grows on deep gypsum-rich sandy soil on eroded mountain slopes between Cayirhan and Nallihan in Ankara. Diagnostic ... -
Differential Requirement For The Atpase Domain Of The Cockayne Syndrome Group B Gene In The Processing Of Uv-Induced Dna Damage And 8-Oxoguanine Lesions In Human Cells
(Oxford Univ Press, 2002)Cockayne syndrome (CS) is a rare inherited human genetic disorder characterized by UV sensitivity, developmental abnormalities and premature aging. The cellular and molecular phenotypes of CS include increased sensitivity ... -
Effect of Topically Applied Charged Particles on Healing of Colonic Anastomoses
(Amer Medical Assoc, 2002)Hypothesis: Various forms of electrical stimulation can improve wound healing in different tissues, but their application to gastrointestinal tract healing has not been investigated. We assumed that positively charged ... -
Diagnostic Implications Of Telomerase Activity In Pleural Effusions
(European Respiratory Soc Journals Ltd, 2003)The aim of the present study was to investigate the diagnostic efficacy of telomerase activity for discrimination of malignant and benign pleural effusions. Pleural effusions were collected from 109 consecutive patients ... -
Solid-Phase Enzyme Modification Via Affinity Chromatography
(Elsevier Science Bv, 2003)In the present study antileukemic enzyme L-asparaginase (ASNase) and catalase (as a model enzyme) were modified in solid-phase with activated polyethylene glycol (PEG,) by using ligand-immobilized affinity column systems ... -
Effects Of Rosiglitazone Treatment On The Pentose Phosphate Pathway And Glutathione-Dependent Enzymes In Liver And Kidney Of Rats Fed A High-Fat Diet
(Elsevier Science Inc, 2004)Background: Animals fed high-fat diets have been shown to develop hyperglycemia, insulin resistance, hyperlipidemia, and moderate obesity, which resemble the human metabolic syndrome. Obesity, the metabolic syndrome, and ... -
In Vivo Inhibition Of Lung Cancer By Grn163L: A Novel Human Telomerase Inhibitor
(Amer Assoc Cancer Research, 2005)Differential regulation of telomerase activity in normal and tumor cells provides a rationale for the design of new classes of telomerase inhibitors. The telomerase enzyme complex presents multiple potential sites for the ... -
Xeroderma Pigmentosum Complementation Group E Protein (Xpe/Ddb2): Purification Of Various Complexes Of Xpe And Analyses Of Their Damaged Dna Binding And Putative Dna Repair Properties
(Amer Soc Microbiology, 2005)Xeroderma pigmentosum is characterized by increased sensitivity of the affected individuals to sunlight and light-induced skin cancers and, in some cases, to neurological abnormalities. The disease is caused by a mutation ... -
Effects Of Cadmium And Zinc Ions On Purified Lamb Kidney Cortex Glucose-6-Phosphate Dehydrogenase Activity
(Taylor & Francis Ltd, 2006)Glucose-6-phosphate dehydrogenase (G-6-PD) is the first enzyme in the pentose phosphate pathway. Cadmium is a toxic heavy metal that inhibits several enzymes. Zinc is an essential metal but overdoses of zinc have toxic ... -
Misincorporation Of Free M-Tyrosine Cytotoxic Mechanism For Oxidized A Into Cellular Proteins: A Potential Amino Acids
(Portland Press Ltd, 2006)In vitro studies demonstrate that the hydroxyl radical converts L-phenylalanine into in-tyrosine, an unnatural isomer of L-tyrosine. Quantification of m-tyrosine has been widely used as an index of oxidative damage in ... -
Sedative Effect of Centranthus Longiflorus Ssp Longiflorus in Rats and the Influence of Adrenalectomy on Its Effect
(Pharmaceutical Soc Japan, 2007)Sedative effect of the aqueous extract of Centranthus longiflorus ssp. longiflorus (Cle-1) on intact and adrenalectomized rats was investigated using a thiopental sleeping test to clarify the relationship of this effect ... -
Increased Levels Of Nitric Oxide, Cortisol And Adrenomedullin In Patients With Chronic Schizophrenia
(Karger, 2007)Objective: To investigate the levels of serum cortisol, dehydroepiandrosterone sulfate (DHEA-S), nitric oxide (NO) and adrenomedullin (AM) in schizophrenic patients. Subjects and Methods: Sixty-six male patients with chronic ...
