• A Cadaveric Histological Investigation of the Prostate with Three-Dimensional Reconstruction for Better Results in Continence and Erectile Function After Radical Prostatectomy 

      Özdemir, M. B.; Eskicorapci, S. Y.; Baydar, D. E.; Cumhur, M.; Önderoglu, S.; Özen, H. (Nature Publishing Group, 2007)
      In this study our aim is to increase the understanding of the prostate and related organs anatomy for better continence and erectile function results after urological surgery. Prostate and related organs were dissected ...
    • A Novel Graft Option After Pterygium Excision: Platelet-Rich Fibrin for Conjunctivoplasty 

      Cakmak, H. B.; Can, G. Dereli; Can, M. E.; Cagil, N. (Nature Publishing Group, 2017)
      Purpose To compare the surgical results, complications, and recurrence rates of primary pterygium excision with conjunctival autografts (CA) vs platelet-rich fibrin (PRF) grafts. Patients and methods A total of 35 eyes of ...
    • Abdominal Distention and Peritoneal Effusion in a Female Swiss Albino Mouse 

      Kosemehmetoglu, Kemal; Ulu, Nadir; Iskit, Alper B.; Arıkan, Pınar F.; Sokmensuer, Cenk; Onur, Rustu; Guc, M. Oguz (Nature Publishing Group, 2007)
    • Amblyopia And Sensory Features At Initial Presentation of Brown Syndrome: An Issue to Recognize 

      Sekeroglu, H. T.; Muz, E.; Sanac, A. S.; Sener, E. C.; Arslan, U. (Nature Publishing Group, 2013)
      Purpose To investigate the frequency of amblyopia and sensory features at initial presentation in patients who had unilateral congenital Brown syndrome (BS) and to identify the potential risk factors for amblyopia in BS. ...
    • Cpg Methylation In The Fhit Regulatory Region: Relation To Fhit Expression In Murine Tumors 

      Han, SY; Iliopoulos, D; Druck, T; Guler, G; Grubbs, CJ; Pereira, M; Zhang, ZQ; You, M; Lubet, RA; Fong, LYY; Huebner, K (Nature Publishing Group, 2004)
      To determine if: (1) 5' CpG island methylation is related to Fhit inactivation; (2) there are tumor or carcinogen-specific methylation patterns, we examined 35 CpG sites in the promoter, exon and intron 1 of the mouse Fhit ...
    • De Novo Mutations In Smchd1 Cause Bosma Arhinia Microphthalmia Syndrome And Abrogate Nasal Development 

      Gordon, Christopher T.; Xue, Shifeng; Yigit, Goekhan; Filali, Hicham; Chen, Kelan; Rosins, Nadine; Yoshiura, Koh-ichiro; Oufadem, Myriam; Beck, Tamara J.; McGowan, Ruth; Magee, Alex C.; Altmueller, Janine; Dion, Camille; Thiele, Holger; Gurzau, Alexandra D.; Nuernberg, Peter; Meschede, Dieter; Muehlbauer, Wolfgang; Okamoto, Nobuhiko; Varghese, Vinod; Irving, Rachel; Sigaudy, Sabine; Williams, Denise; Ahmed, S. Faisal; Bonnard, Carine; Kong, Mung Kei; Ratbi, Ilham; Fejjal, Nawfal; Fikri, Meriem; Elalaoui, Siham Chafai; Reigstad, Hallvard; Bole-Feysot, Christine; Nitschke, Patrick; Ragge, Nicola; Levy, Nicolas; Tuncbilek, Goekhan; Teo, Audrey S. M.; Cunningham, Michael L.; Sefiani, Abdelaziz; Kayserili, Huelya; Murphy, James M.; Chatdokmaiprai, Chalermpong; Hillmer, Axel M.; Wattanasirichaigoon, Duangrurdee; Lyonnet, Stanislas; Magdinier, Frederique; Javed, Asif; Blewitt, Marnie E.; Amiel, Jeanne; Wollnik, Bernd; Reversade, Bruno (Nature Publishing Group, 2017)
      Bosma arhinia microphthalmia syndrome (BAMS) is an extremely rare and striking condition characterized by complete absence of the nose with or without ocular defects. We report here that missense mutations in the epigenetic ...
    • Genetic Association Study Of Exfoliation Syndrome Identifies A Protective Rare Variant At Loxl1 And Five New Susceptibility Loci 

      Aung, Tin; Ozaki, Mineo; Lee, Mei Chin; Schlotzer-Schrehardt, Ursula; Thorleifsson, Gudmar; Mizoguchi, Takanori; Igo, Robert P; Jr.; Haripriya, Aravind; Williams, Susan E.; Astakhov, Yury S.; Orr, Andrew C.; Burdon, Kathryn P.; Nakano, Satoko; Mori, Kazuhiko; Abu-Amero, Khaled; Hauser, Michael; Li, Zheng; Prakadeeswari, Gopalakrishnan; Bailey, Jessica N. Cooke; Cherecheanu, Alina Popa; Kang, Jae H.; Nelson, Sarah; Hayashi, Ken; Manabe, Shin-ichi; Kazama, Shigeyasu; Zarnowski, Tomasz; Inoue, Kenji; Irkec, Murat; Coca-Prados, Miguel; Sugiyama, Kazuhisa; Jarvela, Irma; Schlottmann, Patricio; Lerner, S. Fabian; Lamari, Hasnaa; Nilgun, Yildirim; Bikbov, Mukharram; Park, Ki Ho; Cha, Soon Cheol; Yamashiro, Kenji; Zenteno, Juan C.; Jonas, Jost B.; Kumar, Rajesh S.; Perera, Shamira A.; Chan, Anita S. Y.; Kobakhidze, Nino; George, Ronnie; Vijaya, Lingam; Do, Tan; Edward, Deepak P.; de Juan Marcos, Lourdes; Pakravan, Mohammad; Moghimi, Sasan; Ideta, Ryuichi; Bach-Holm, Daniella; Kappelgaard, Per; Wirostko, Barbara; Thomas, Samuel; Gaston, Daniel; Bedard, Karen; Greer, Wenda L.; Yang, Zhenglin; Chen, Xueyi; Huang, Lulin; Sang, Jinghong; Jia, Hongyan; Jia, Liyun; Qiao, Chunyan; Zhang, Hui; Liu, Xuyang; Zhao, Bowen; Wang, Ya-Xing; Xu, Liang; Leruez, Stephanie; Reynier, Pascal; Chichua, George; Tabagari, Sergo; Uebe, Steffen; Zenkel, Matthias; Berner, Daniel; Mossboeck, Georg; Weisschuh, Nicole; Hoja, Ursula; Welge-Luessen, Ulrich-Christoph; Mardin, Christian; Founti, Panayiota; Chatzikyriakidou, Anthi; Pappas, Theofanis; Anastasopoulos, Eleftherios; Lambropoulos, Alexandros; Ghosh, Arkasubhra; Shetty, Rohit; Porporato, Natalia; Saravanan, Vijayan; Venkatesh, Rengaraj; Shivkumar, Chandrashekaran; Kalpana, Narendran; Sarangapani, Sripriya; Kanavi, Mozhgan R.; Beni, Afsaneh Naderi; Yazdani, Shahin; Lashay, Alireza; Naderifar, Homa; Khatibi, Nassim; Fea, Antonio; Lavia, Carlo; Dallorto, Laura; Rolle, Teresa; Frezzotti, Paolo; Paoli, Daniela; Salvi, Erika; Manunta, Paolo; Mori, Yosai; Miyata, Kazunori; Higashide, Tomomi; Chihara, Etsuo; Ishiko, Satoshi; Yoshida, Akitoshi; Yanagi, Masahide; Kiuchi, Yoshiaki; Ohashi, Tsutomu; Sakurai, Toshiya; Sugimoto, Takako; Chuman, Hideki; Aihara, Makoto; Inatani, Masaru; Miyake, Masahiro; Gotoh, Norimoto; Matsuda, Fumihiko; Yoshimura, Nagahisa; Ikeda, Yoko; Ueno, Morio; Sotozono, Chie; Jeoung, Jin Wook; Sagong, Min; Park, Kyu Hyung; Ahn, Jeeyun; Cruz-Aguilar, Marisa; Ezzouhairi, Sidi M.; Rafei, Abderrahman; Chong, Yaan Fun; Ng, Xiao Yu; Goh, Shuang Ru; Chen, Yueming; Yong, Victor H. K.; Khan, Muhammad Imran; Olawoye, Olusola O.; Ashaye, Adeyinka O.; Ugbede, Idakwo; Onakoya, Adeola; Kizor-Akaraiwe, Nkiru; Teekhasaenee, Chaiwat; Suwan, Yanin; Supakontanasan, Wasu; Okeke, Suhanya; Uche, Nkechi J.; Asimadu, Ifeoma; Ayub, Humaira; Akhtar, Farah; Kosior-Jarecka, Ewa; Lukasik, Urszula; Lischinsky, Ignacio; Castro, Vania; Perez Grossmann, Rodolfo; Megevand, Gordana Sunaric; Roy, Sylvain; Dervan, Edward; Silke, Eoin; Rao, Aparna; Sahay, Priti; Fornero, Pablo; Cuello, Osvaldo; Sivori, Delia; Zompa, Tamara; Mills, Richard A.; Souzeau, Emmanuelle; Mitchell, Paul; Wang, Jie Jin; Hewitt, Alex W.; Coote, Michael; Crowston, Jonathan G.; Astakhov, Sergei Y.; Akopov, Eugeny L.; Emelyanov, Anton; Vysochinskaya, Vera; Kazakbaeva, Gyulli; Fayzrakhmanov, Rinat; Al-Obeidan, Saleh A.; Owaidhah, Ohoud; Aljasim, Leyla Ali; Chowbay, Balram; Foo, Jia Nee; Soh, Raphael Q.; Sim, Kar Seng; Xie, Zhicheng; Cheong, Augustine W. O.; Mok, Shi Qi; Soo, Hui Meng; Chen, Xiao Yin; Peh, Su Qin; Heng, Khai Koon; Husain, Rahat; Ho, Su-Ling; Hillmer, Axel M.; Cheng, Ching-Yu; Escudero-Dominguez, Francisco A.; Gonzalez-Sarmiento, Rogelio; Martinon-Torres, Frederico; Salas, Antonio; Pathanapitoon, Kessara; Hansapinyo, Linda; Wanichwecharugruang, Boonsong; Kitnarong, Naris; Sakuntabhai, Anavaj; Nguyn, Hip X.; Nguyn, Giang T. T.; Nguyn, TrNh V.; Zenz, Werner; Binder, Alexander; Klobassa, Daniela S.; Hibberd, Martin L.; Davila, Sonia; Herms, Stefan; Nothen, Markus M.; Moebus, Susanne; Rautenbach, Robyn M.; Ziskind, Ari; Carmichael, Trevor R.; Ramsay, Michele; Alvarez, Lydia; Garcia, Montserrat; Gonzalez-Iglesias, Hector; Rodriguez-Calvo, Pedro P.; Fernandez-Vega Cueto, Luis; Oguz, Cilingir; Tamcelik, Nevbahar; Atalay, Eray; Batu, Bilge; Aktas, Dilek; Kasim, Burcu; Wilson, M. Roy; Coleman, Anne L.; Liu, Yutao; Challa, Pratap; Herndon, Leon; Kuchtey, Rachel W.; Kuchtey, John; Curtin, Karen; Chaya, Craig J.; Crandall, Alan; Zangwill, Linda M.; Wong, Tien Yin; Nakano, Masakazu; Kinoshita, Shigeru; den Hollander, Anneke I.; Vesti, Eija; Fingert, John H.; Lee, Richard K.; Sit, Arthur J.; Shingleton, Bradford J.; Wang, Ningli; Cusi, Daniele; Qamar, Raheel; Kraft, Peter; Pericak-Vance, Margaret A.; Raychaudhuri, Soumya; Heegaard, Steffen; Kivela, Tero; Reis, Andre; Kruse, Friedrich E.; Weinreb, Robert N.; Pasquale, Louis R.; Haines, Jonathan L.; Thorsteinsdottir, Unnur; Jonasson, Fridbert; Allingham, R. Rand; Milea, Dan; Ritch, Robert; Kubota, Toshiaki; Tashiro, Kei; Vithana, Eranga N.; Micheal, Shazia; Topouzis, Fotis; Craig, Jamie E.; Dubina, Michael; Sundaresan, Periasamy; Stefansson, Kari; Wiggs, Janey L.; Pasutto, Francesca; Khor, Chiea Chuen (Nature Publishing Group, 2017)
      Exfoliation syndrome (XFS) is the most common known risk factor for secondary glaucoma and a major cause of blindness worldwide. Variants in two genes, LOXL1 and CACNA1A, have previously been associated with XFS. To further ...
    • High Prevalence Of Tert Promoter Mutations In Primary Squamous Cell Carcinoma Of The Urinary Bladder 

      Cowan, Morgan; Springer, Simeon; Nguyen, Doreen; Taheri, Diana; Guner, Gunes; Rodriguez, Maria Angelica Mendoza; Wang, Yuxuan; Kinde, Isaac; VandenBussche, Christopher J.; Olson, Matthew T.; Cunha, Isabela; Fujita, Kazutoshi; Ertoy, Dilek; Bivalacqua, Trinity J.; Kinzler, Kenneth; Vogelstein, Bert; Netto, George J.; Papadopoulos, Nickolas (Nature Publishing Group, 2016)
      TERT promoter mutations (TERT-mut) are detectable in the majority of urothelial carcinomas. The detection of TERT-mut in urine is under investigation as a potential urine-based molecular-screening assay for bladder cancer. ...
    • Horizontal Muscle Transposition Or Oblique Muscle Weakening For The Correction Of V Pattern? 

      Sekeroglu, H. T.; Turan, K. E.; Uzun, S.; Sener, E. C.; Sanac, A. S. (Nature Publishing Group, 2014)
      Purpose To report and to analyze the efficacy of horizontal rectus muscle transposition and inferior oblique muscle weakening in terms of pattern correction for patients with V pattern. Methods The review of the medical ...
    • In Vivo Confocal Microscopic Evaluation Of Keratic Precipitates And Endothelial Morphology In Fuchs' Uveitis Syndrome 

      Mocan, M. C.; Kadayifcilar, S.; Irkec, M. (Nature Publishing Group, 2012)
      Purpose To evaluate the endothelial cell layer in patients with Fuchs' uveitis syndrome (FUS) with respect to the type and distribution of keratic precipitates (KP), endothelial cell morphology, and endothelial cell density ...
    • Intraradicular Disc Herniations in the Lumbar Spine and a New Classification of Intradural Disc Herniations 

      Mut, M; Berker, M; Palaoglu, S (Nature Publishing Group, 2001)
      Study design: A case report of intraradicular disc herniation. Intraradicular disc herniation is a special type of intradural disc hernations. In this report, we present the tenth case of intraradicular lumbar disc herniation ...
    • Intravitreal Pegaptanib Sodium for Choroidal Neovascularisation Secondary to Age-Related Macular Degeneration: Pan-European Experience 

      Sivaprasad, S.; Hykin, P.; Saeed, A.; Beatty, S.; Grisanti, S.; Staurenghi, G.; Olea, J. L.; Campos, A.; Barbosa, A.; Rito, L.; Silva, R.; Faria, R.; Eldem, B.; Kadayifcilar, S.; Kolar, P.; Feucht, N.; Maestroni, L. (Nature Publishing Group, 2010)
      Purpose To evaluate visual outcomes in patients with neovascular age-related macular degeneration (NV-AMD) who were treated with pegaptanib sodium in European clinical ophthalmology practices. Methods Thirteen centres in ...
    • Mean Intraocular Pressure and Progression Based on Corneal Thickness in Patients with Ocular Hypertension 

      Konstas, A. G. P.; Irkec, M. T.; Teus, M. A.; Cvenkel, B.; Astakhov, Y. S.; Sharpe, E. D.; Hollo, G.; Mylopoulos, N.; Bozkurt, B.; Pizzamiglio, C.; Potyomkin, V. V.; Alemu, A. M.; Nasser, Q. J.; Stewart, J. A.; Stewart, W. C. (Nature Publishing Group, 2009)
      Purpose To determine the incidence of glaucomatous progression at mean intraocular pressure (IOP) levels in patients with ocular hypertension (OHT). Methods A retrospective, multicentre, cohort analysis of 230 OHT patients ...
    • Ocular Injuries From Improvised Explosive Devices 

      Erdurman, F. C.; Hurmeric, V.; Gokce, G.; Durukan, A. H.; Sobaci, G.; Altinsoy, H. I. (Nature Publishing Group, 2011)
      Purpose To document the characteristics, treatments, and anatomical and functional outcomes of patients with ocular trauma from improvised explosive devices (IEDs). Methods Retrospective review of ocular injuries caused ...
    • Reduction of Qm Protein Expression Correlates with Tumor Grade in Prostatic Adenocarcinoma 

      Altinok, G; Powell, IJ; Che, M; Hormont, K; Sarkar, FH; Sakr, WA; Grignon, D; Liao, DJ (Nature Publishing Group, 2006)
      The QM protein is a transcription cofactor inhibiting the activity of AP-1 transcription factors and is also a ribosomal protein participating in protein synthesis. While protein synthesis is known to be increased in many ...
    • Targeting Plk1 Overcomes T-Dm1 Resistance Via Cdk1-Dependent Phosphorylation and Inactivation Of Bcl-2/Xl in Her2-Positive Breast Cancer 

      Saatçi, Özge; Borgoni, Simone; Akbulut, Özge; Durmuş, Selvi; Raza, Umar; Eyüpoğlu, Erol; Alkan, Can; Akyol, Aytekin; Kütük, Özgür; Wiemann, Stefan; Şahin, Özgür (Nature Publishing Group, 2018)
      Trastuzumab-refractory, HER2 (human epidermal growth factor receptor 2)-positive breast cancer is commonly treated with trastuzumab emtansine (T-DM1), an antibody-drug conjugate of trastuzumab and the microtubule-targeting ...
    • The Role Of Apoptosis In Blepharoptosis 

      Sahli, E.; Hosal, B. M.; Zilelioglu, G.; Dincer, N.; Tezel, G. G. (Nature Publishing Group, 2013)
      Purpose The purpose of this study is to evaluate the role of apoptosis in the pathogenesis of blepharoptosis. Patients and methods Forty-five eyelids of 43 consecutive patients (16 female, 27 males) that underwent levator ...
    • The Znf304-Integrin Axis Protects Against Anoikis In Cancer 

      Aslan, Burcu; Monroig, Paloma; Hsu, Ming-Chuan; Pena, Guillermo Armaiz; Rodriguez-Aguayo, Cristian; Gonzalez-Villasana, Vianey; Rupaimoole, Rajesha; Nagaraja, Archana Sidalaghatta; Mangala, Selanere; Han, Hee-Dong; Yuca, Erkan; Wu, Sherry Y.; Ivan, Cristina; Moss, Tyler J.; Ram, Prahlad T.; Wang, Huamin; Gol-Chambers, Alexandra; Ozkayar, Ozgur; Kanlikilicer, Pinar; Fuentes-Mattei, Enrique; Kahraman, Nermin; Pradeep, Sunila; Ozpolat, Bulent; Tucker, Susan; Hung, Mien-Chie; Baggerly, Keith; Bartholomeusz, Geoffrey; Calin, George; Sood, Anil K.; Lopez-Berestein, Gabriel (Nature Publishing Group, 2015)
      Ovarian cancer (OC) is a highly metastatic disease, but no effective strategies to target this process are currently available. Here, an integrative computational analysis of the Cancer Genome Atlas OC data set and ...
    • Tle1 Expression Is Not Specific For Synovial Sarcoma: A Whole Section Study Of 163 Soft Tissue And Bone Neoplasms 

      Kosemehmetoglu, Kemal; Vrana, Julie A.; Folpe, Andrew L. (Nature Publishing Group, 2009)
      TLE1, a transcriptional repressor essential in hematopoiesis, neuronal differentiation and terminal epithelial differentiation, has recently been shown in a single tissue microarray study to be a highly sensitive and ...
    • X-Linked Recessive Inheritance Of Radial Ray Deficiencies In A Family With Four Affected Males 

      Galjaard, RJH; Kostakoglu, N; Hoogeboom, JJM; Breedveld, GJ; van der Linde, HC; Hovius, SER; Oostra, BA; Sandkuijl, LA; Akarsu, AN; Heutink, P (Nature Publishing Group, 2001)
      Radial ray deficiencies are frequently associated with additional clinical anomalies and have a heterogeneous aetiology. X-linked forms are extremely rare. We report a family in which four male relatives show bilateral ...