Browsing Cerrahi Tıp Bilimleri Bölümü by Publisher "Amer Assoc Cancer Research"

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A Role for Endothelin-2 and Its Receptors in Breast Tumor Cell Invasion

Grimshaw, MJ; Hagemann, T; Ayhan, A; Gillett, CE; Binder, C; Balkwill, FR (Amer Assoc Cancer Research, 2004)

We have studied the role of endothelins (ET-1, ET-2 and ET-3) and ET receptors (ET-RA and ET-RB) in the invasive capacity of breast tumor cells, which express ET-I and ET-2 as well as ET-RA and ET-RB. Of five human breast ...
The Inflammatory Cytokine Tumor Necrosis Factor-Alpha Generates An Autocrine Tumor-Promoting Network In Epithelial Ovarian Cancer Cells

Kulbe, Hagen; Thompson, Richard; Wilson, Julia L.; Robinson, Stephen; Hagemann, Thorsten; Fatah, Rewas; Gould, David; Ayhan, Ayse; Balkwill, Frances (Amer Assoc Cancer Research, 2007)

Constitutive expression of the inflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) is characteristic of malignant ovarian surface epithelium. We investigated the hypothesis that this autocrine action of TNF-alpha ...