Browsing Cerrahi Tıp Bilimleri Bölümü by Title
Now showing items 228-247 of 1040
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Damak Yarıklarının İn Situ Doku Mühendisliği ile Onarımı: Alveolar Yarık Hayvan Modeli Oluşturulması ve Farklı Rejimlerde Biyobozunur Doku Iskeleleri ile Onarımı
(Tıp Fakültesi, 2014)In this study, the tricalcium phosphate polymer, a tissue scaffold known for its direct effects on tissue healing, and that is used commonly in bone defect models, was upgraded by adding collagen by the Hacettepe University ... -
De Novo Mutations In Smchd1 Cause Bosma Arhinia Microphthalmia Syndrome And Abrogate Nasal Development
(Nature Publishing Group, 2017)Bosma arhinia microphthalmia syndrome (BAMS) is an extremely rare and striking condition characterized by complete absence of the nose with or without ocular defects. We report here that missense mutations in the epigenetic ... -
Decreased Catalytic Activity And Altered Activation Properties Of Pde6C Mutants Associated With Autosomal Recessive Achromatopsia
(Oxford Univ Press, 2011)Mutations in the gene encoding the catalytic subunit of the cone photoreceptor phosphodiesterase (PDE6C) have been recently reported in patients with autosomal recessive inherited achromatopsia (ACHM) and early-onset cone ... -
Decreased Keratocyte Density And Central Corneal Thickness In Primary Open-Angle Glaucoma Patients Undergoing Treatment With Topical Prostaglandin Analogues
(2015)Purpose: To evaluate whether prostaglandin (PG) analogue use is associated with alterations in keratocyte density and central corneal thickness (CCT) in subjects with primary open-angle glaucoma (POAG). Materials and ... -
Decreased Serum Paraoxonase 1 (Pon1) Activity: An Additional Risk Factor For Atherosclerotic Heart Disease In Patients With Pcos?
(Oxford Univ Press, 2006)BACKGROUND: Patients with polycystic ovary syndrome (PCOS) may have an increased risk for the development of hypertension and atherosclerotic heart disease (AHD), the pathophysiological mechanisms of which are not clear. ... -
Deneysel Epilepsi Modelinde Prolaktin Hormon Düzeyinin Hipokampüs Üzerine Etkisi
(Tıp Fakültesi, 2013)Epilepsy is the one of the most common type of the cerebral diseases. Seizure is defined as the sudden, abnormal and unexpected electrical discharge that results in clinical change and generally they are short episodes ... -
Deneysel İkinci Derece Derin Yanık Modelinde Kültüre Edilmemiş Hücre Spreyi Kullanımı
(Tıp Fakültesi, 2019)NURAL SK. The Use of Non-Cultured Cell Spray in Experimental Deep Second Degree Burn Model. Hacettepe University Faculty of Medicine, Thesis in General Surgery, Ankara 2019. Most of the burn injuries can be treated in ... -
Deneysel Kafa Travması Modelinde Intraventriküler Antisens Oligonükleotid Injeksiyonu ile Aquaporin-4 Ün Baskılanmasının Beyin Ödemi Üzerine Etkisi
(Tıp Fakültesi, 2013)Objective: Aquaporin-4 (AQP4) plays an important role in the regulation of water balance in the brain. In this study, inhibition of AQP4 synthesis and decrease in brain edema following intraventricular injection of ... -
Deneysel Kist Hidatik ve Meme Kanseri Modelinde Gelişen İmmün Baskılanma Karaciğeri Hedef Organ Haline Getirir
(Tıp Fakültesi, 2014)Turkey is included in the endemic regions for Echinococcus granulosus infections. It is believed that due to its antigenic similarity Liver is the target organ in many cancers. Strong immune responses are one of the factors ... -
Deneysel Kronik Karaciğer Hastalığı Oluşturulan Sıçanlarda Sentetik Yama Kullanımının Cerrahi Alan Enfeksiyonu Üzerine Etkisi
(Tıp Fakültesi, 2017-12-25)In patients with liver cirrhosis, the risk of infection that develops in the surgical field after usage of mesh for the anterior wall hernia repair of the abdomen, thus the risk of failure of the operation is still a matter ... -
Deneysel Meme Kanseri Modelinde Karaciğer Rezeksiyonunun İmmünolojik Etkileri
(Tıp Fakültesi, 2017-12-26)Liver is the third common solid organ of breast cancer metastasis. If it is left untreated, the overall survival is only 4-8 months. Even though, liver resection for liver metastasis is shown to improve the survival, ... -
Deneysel Meme Kanseri Modelinde Splenektominin İmmünolojik Etkisi
(Tıp Fakültesi, 2015)Sevmiş M. Immunologic effects of splenectomy in experimental breast carcinoma model. Hacettepe University School of Medicine, General Surgery Residency Thesis, ANKARA 2015. Immune system plays an important role in the ... -
Deneysel Omurilik Transeksiyon Modelinde Erişkin İnsan Mezenşim Kaynaklı Kök Hücrelerin Citosan Tüpler İçerisinde İmplantasyonunun Etkisi ve Sonuçları
(Tıp Fakültesi, 2012)Mesenchyme originated stem cells that are isolated from adult mesenchymal tissues were transplanted to damaged spinal cords in experimental animal models with various levels of axonal regeneration and functional recovery ... -
Deneysel Siyatik Sinir Yaralanmasında Poli(3-Hidroksibütirat) (Phb) Vechitosan Kaplı Tübüler Greftler ile Birlikte Mezenşimal Kök Hücre Kullanımının Aksonalrejenerasyona Etkisi
(Tıp Fakültesi, 2013)The gold standard in the treatment of peripheral neuronal injury is end to end anastomosis of the nerve endings, but in case of tension or segmental neuronal tissue loss, neuronal garfts must be used. Disadvantages of ... -
Deneysel Sıçan Beyin Tümörü Modelinde Polilaktik–Ko-Glikolik Asit (Plga) Nanopartikülüne Yüklü Curcuminin Etkisinin Izlenmesi
(Tıp Fakültesi, 2014)Glioblastoma multiforme (GBM ) is one of the most malignant brain tumors. With radical surgery, radiotherapy and chemotherapy median survival is 12-14 months. Due to the infiltrative and invasive nature of glioblastoma may ... -
Deneysel Sıçan Yüksek Dereceli Beyin Tümörü Modelinde İnsan Kaynaklı Mezenşimal Kök Hücre Göçünün İzlenmesi
(Tıp Fakültesi, 2013)Objective Glioblastoma Multiforme (GBM) is one of the most malign tumors. Survival rates are too short and quality of life is poor after the diagnosis and the treatment. With radical surgery, chemotherapy and radiotherapy ... -
Deri Eki Tümörlerinin Histopatolojik Açıdan Değerlendirilmesi ve Wnt Yolağı ile İlişkisinin Araştırılması
(Tıp Fakültesi, 2013)The aim of this study is histopathological evaluation and classification of cutaneous adnexal tumors, and identification of the relationship between these tumors and Wnt/beta-katenin pathway by immunohistochemistry. One ... -
Detection Of Telomerase Activity In Bronchial Lavage As An Adjunct To Cytological Diagnosis In Lung Cancer
(Elsevier Science Bv, 2003)Objective: Definitive diagnosis of lung cancer with conventional methods may sometimes be difficult in clinical practice. Telomerase is a ribonucleoprotein DNA polymerase that maintains the telomeric region of chromosomes ...
