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Expression Profiles Of The Individual Genes Corresponding To The Genes Generated By Cytotoxicity Experiments With Bortezomib In Multiple Myeloma
(2016)
Objective: Multiple myeloma (MM) is currently incurable due to refractory disease relapse even under novel anti-myeloma treatment. In silico studies are effective for key decision making during clinicopathological battles ...
Local Renin-Angiotensin System in Normal Hematopoietic and Multiple Myeloma-Related Progenitor Cells
(2014)
Objective: The prominent functions of the local renin-angiotensin system (RAS) in primitive hematopoiesis further support the hypothesis that local autocrine bone marrow RAS could also be active in neoplastic hematopoiesis. ...
Pharmacobiological Approach for the Clinical Development of Ruxolitinib in Myeloproliferative Neoplasms
(2015)
Ruxolitinib, a JAK1 and JAK2 inhibitor drug, has recently been approved for the treatment of patients with high- or intermediate-risk myelofibrosis with symptomatic splenomegaly. Ruxolitinib is the first clinically useful ...
Co-Expression Of T(15;17) And T(8;21) In A Case Of Acute Promyelocytic Leukemia: Review Of The Literature
(2013)
Additional chromosomal abnormalities in acute myelogenous leukemia have been identified as one of the most important prognostic factors. Favorable chromosomal changes such as t(8;21), inv(16), and t(15;17) are associated ...
The Prognosis Of Adult Burkitt’S Cell Leukemia In Real-Life Clinical Practice
(2016)
Objective: Many studies reported an improved prognosis in patients with Burkitt’s lymphoma obviating the need of stem cell transplantation. However, prognosis of the advanced disease [i.e. Burkitt’s cell leukemia (BCL)] ...
Unusual Extramedullary Recurrence And Renal Relapse Despite Complete Chimerysm After Allografting In Ph+ All
(Akad Doktorlar Yayınevi, 2012)
Extramedullary recurrences with or without bone marrow involvement are reported in up to a half of leukemic relapses after bone marrow transplantation. Extramedullary relapse of acute lymphoblastic leukemia (ALL) in the ...
Hacettepe Dahiliye Ders Kitabı 2
(Hacettepe Üniversitesi, 2020)
Ondokuzuncu yüzyılın tıp literatürü, korku filmi gibidir. Hekimlerin, ellerine geçirdikleri her şeyi,
akıllarına gelen her yöntemi tedavi için kullandıkları görülür. Bilgiye değil, kulaktan dolma duyumlara
dayanan, “içten ...