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Skewed X Chromosome Inactivation in Blood Cells of Women with Scleroderma
(Wiley, 2005)
Objective. Scleroderma (SSc) is an autoimmune disease of unknown etiology. The disease is 3-8 times more frequent in women than in men. The role of X chromosome inactivation (XCI) in the predisposition of women to autoinimunity ...