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Alpha-Synuclein Aggregation Induced By Brief Ischemia Negatively Impacts Neuronal Survival in Vivo: A Study in [A30P] Alpha-Synuclein Transgenic Mouse
(Sage Publications Inc, 2011)
Alpha-synuclein oligomerization and aggregation are considered to have a role in the pathogenesis of neurodegenerative diseases. However, despite numerous in vitro studies, the impact of aggregates in the intact brain is ...
Systemically Administered Brain-Targeted Nanoparticles Transport Peptides Across the Blood-Brain Barrier and Provide Neuroprotection
(Nature Publishing Group, 2015)
Although growth factors and anti-apoptotic peptides have been shown to be neuroprotective in stroke models, translation of these experimental findings to clinic is hampered by limited penetration of peptides to the brain. ...