Pron Masada Stereotaktik Vakumlu Biyopsi Yapılan Mikrokalsifikasyonların Mamografik Özelliklerinin Patoloji Bulgularıyla Karşılaştırılması

Abstract

Comparison of Mamographic Findings with Pathology Results of Microcalcifications which are excised by Stereotactic Vacuum Assisted Biopsy on Prone Table, Hacettepe University Faculty of Medicine, Thesis in Radiology, Ankara, 2014. The purpose of this thesis is to evaluate lesions (n=119) which were detected by mamographycally and biopsied with stereotactic vacuum assisted biopsy device on prone table between March 2010-July 2014 in Hacettepe University Faculty of Medicine Breast Imaging Section at Departmant of Radiology. BI-RADS categories before vacuum assisted biopsy were compared with pathology results after vacuum assisted biopsy and after operation. We compared our data with literature for assesment of efficiency and performance of our breast imaging unit. Lesions which were biopsied on prone table were only microcalcifications and both microcalcifications and nodules. BI-RADS categories was determined before vacuum assisted biopsy according to lesions mamographic features (microcalcification shape and distribution pattern, according shape and margin with accompanying masses). Statistical analysis was performed using SPSS software. The most frequent lesion type for stereotactic vacuum assisted biopsy was performed was microcalcifications. They were identified in 96,6%. Patients have upgrade the number of removed calcifications (logaritmic) were significantly higher than cases which don't have upgrade situation statistically (t=3,358; p=0,001). Stereotactic vacuum assisted biopsy revealed that 52,1% of lesions were benign and 47,9% were malignant. After vacuum assisted stereotactic biopsy 61 patients were operated. In 10 of them 16,3% the final histopathologic diagnosis was benign, in 51 of them 83,7% were malignant. ADH frequency was found to be 6,7%. In our study none of the ADH upgraded to malignant lesions. After vacuum assisted biopsy the frequency of in situ carcinoma was 37,8%. The upgrade rate of in situ carcinoma to invasive carcinoma was %23,8. False negative diagnostic ratio was % 3,2. In conclusion, vacuum assisted biopsy is a succesfull technique with low failure rate for calcifications that are nonpalpable and have no ultrasonographic findings and in case of existing nodules.