Ara
Toplam kayıt 797, listelenen: 11-20
Mycobacterium Tuberculosis Klinik İzolatlarında İlaç Direncinin Multipleks Real-Time Pcr Yöntemiyle Saptanması
(Sağlık Bilimleri Enstitüsü, 2013)
Tuberculosis (TB) is stil one of the most serious threats to human health around the world. Increasing of the drug resistance is one of the main cause of this state. Early diagnosis of drug-resistant TB cases is urgently ...
Fare Miyoblast Hücre Hattında KLF5 Geninin Farklılaşma Sürecine Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2014)
Embryonic development of the skeletal muscle and injury repair share several molecular events such as the myogenic regulatory factors (MRFs) and paired-homeobox transcription factors. Myogenesis is a highly regulated complex ...
Çocukluk Dönemi Steroide Dirençli Nefrotik Sendroma Sebep Olan Yeni Genlerin Bulunması
(Sağlık Bilimleri Enstitüsü, 2012)
Steroid resistant nephrotic syndrome (SRNS), despite being a rare disease, is the second most common cause of end stage kidney failure in childhood and early adulthood. However the heterogeneity and rarity (<1%) of disease ...
Development and Application of Novel Machine Learning Approaches for Rna-Seq Data Classification
(Sağlık Bilimleri Enstitüsü, 2015)
RNA-Seq is a recent and efficient technique that uses the capabilities of next-generation sequencing technology in characterizing and quantifying transcriptomes. This technique has revolutionized the gene-expression profiling ...
Hukuki ve Etik Yönleri ile Biyotıp Araştırmalarında Biyobankalar
(Sağlık Bilimleri Enstitüsü, 2013)
Biobanks are the organizations where biological materials and associated personal information are collected, stored, processed and distributed in a particular systematic. Biobanks provide opportunity to easily obtain enough ...
İnflamatuvar Hücre Göçü Sürecinde Pyrin ve Aktin İle Ilişkili Proteinlerin Moleküler Analizi
(Sağlık Bilimleri Enstitüsü, 2014)
MEFV gene, encodes Pyrin protein, cause familial Mediterranean fever (FMF). Pyrin which is primarily expressed in neutrophils and monocytes, appears to be a regulator of inflammation, but its exact role on FMF pathophysiology ...
Tekrarlı Çapraz Geçişli Deney Uygulamalarında Kişi Sapan Değeri Bulmak için Kullanılan Hotelling T2 Yönteminin Performansının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)
Detection of outlying subject in bioavailability/bioequivalence studies is an important component of data screening process before statistical analysis. Several methods have been proposed for detecting outliers based on ...
PNPLA1 Geninde Mutasyon Saptanan Konjenital Iktiyoz Vakalarında Yağ Damlacıklarının Lipofaji Aracılı Regülasyonunun Incelenmesi
(Sağlık Bilimleri Enstitüsü, 2015)
Patatin Like Phospholipase Domain Containing Protein-1 (PNPLA1) gene mutations are shown to be linked with Autosomal Recessive Congenital Ichthyoses (ARCI). PNPLA1 protein located on phospholipid membrane structure of lipid ...
İzlem Süresi İçerisinde Belirteçlerin Performanslarını Değerlendirmede Zamana Bağlı Roc Eğrisinin Kullanımı
(Sağlık Bilimleri Enstitüsü, 2015)
The ROC (Receiver Operating Characteristic) method commonly used to evaluate the performance of biological markers which often used to help diagnosis and treatment. The performance of the marker should be evaluated with ...
Spinal Müsküler Atrofi Patogenezinde Rol Alan Genetik Düzenleyicilerin İfade Analizi
(Sağlık Bilimleri Enstitüsü, 2013)
Childhood- onset spinal muscular atrophy (SMA) is an autosomal recessive disorder, which leads to alpha motor neuron degeneration. Although 95-98 % of the patients have homozygous deletions in exon 7 and 8 SMN1 gene, ...