Now showing items 1-7 of 7
Evidence For The Control Of Aggrecanases By Insulin And Glucose In Alzheimer'S Disease
(Kure Iletisim Grubu A S, 2014)
Objective: Alzheimer's disease (AD) is a progressive and irreversible central nervous system disease, which slowly destroys cognitive skills and memory, and eventually even the ability to handle the simplest tasks. The ...
Adamts4 And Adamts5 Knockout Mice Are Protected From Versican But Not Aggrecan Or Brevican Proteolysis During Spinal Cord Injury
The chondroitin sulfate proteoglycans (CSPGs) aggrecan, versican, and brevican are large aggregating extracellular matrix molecules that inhibit axonal growth of the mature central nervous system (CNS). ADAMTS proteoglycanases, ...
Pathophysiological Function of Adamts Enzymes on Molecular Mechanism of Alzheimer's Disease
(Int Soc Aging & Disease, 2016)
The extracellular matrix (ECM) is an environment that has various enzymes attended in regeneration and restoration processes which is very important to sustain physiological and biological functions of central nervous ...
Hydrogen Peroxide-Induced Oxidative Damage In Human Chondrocytes: The Prophylactic Effects Of Hypericum Perforatum Linn Extract On Deoxyribonucleic Acid Damage, Apoptosis And Matrix Remodeling By A Disintegrin-Like And Metalloproteinase With Thrombospondin Motifs Proteinases
(Turkish League Against Rheumatism, 2014)
Objectives: This in vitro study aimed to examine the protective roles of Hypericum perforatum Linn (HPL) extract on cell viability, DNA damage, apoptosis and a disintegrin-like and metalloproteinase with thrombospondin ...
The Role Of Adamts1 And Versican In Human Myocardial Infarction: A Postmortem Study
(Oxford Univ Press, 2016)
Objective: To determine the role of a disintegrin and metalloproteinase with thrombospondin type 1 motif (ADAMTS1) and fragmented versican in the myocardial infarction (MI) process in humans and to evaluate the diagnostic ...
Adamts12 Depletion By Insulin In Oums-27 Human Chondrosarcoma Cells
(Turkish League Against Rheumatism, 2015)
Objectives: In this study, we aim to investigate the association between articular damage in diabetes and a disintegrin-like and metalloproteinase with thrombospondin motifs 12 (ADAMTS12) at gene expression and protein ...