Dosya Biçimi"TÜBİTAK" Temel Tıp Bilimleri Bölümü için listeleme
Toplam kayıt 9, listelenen: 1-9
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Cloning Putative Voltage-Gated Calcium Channel Gene in Astacus Leptodactylus and Determination of Structural and Functional Properties of Related Protein
(Sağlık Bilimleri Enstitüsü, 2023)Voltage-gated calcium channels are essential elements in development of many cellular processes like electrical signaling, contraction secretion and gene expression. There has been a fair amount of information about the ... -
Desminin çekirdeğe taşınımının potansiyel mekanizmalarının araştırılması
(Sağlık Bilimleri Enstitüsü, 2024)Kural Mangıt E., Investigation of Potential Mechanisms for Nuclear Transport of Desmin. Hacettepe University, Graduate School of Health Sciences, Ph.D. Thesis in Medical Biology, Ankara, 2024. Studies have shown that ... -
Glukozilseramidaz-Beta Gen Mutasyonlarının Dopaminerjik Nöronlarda α-sinüklein Yıkım Mekanizmaları Üzerindeki Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)Glucosylceramidase-Beta (GBA1) Gene Mutations are the most important risk factor identified for Parkinson's Disease (PD). Clinically, 'mild' GBA1 mutations (such as N370S) associated with non-neuropathic Gaucher Disease ... -
Investigation of the Role of LAP1B in Transcriptional Regulation of Muscle Cells
(Sağlık Bilimleri Enstitüsü, 2021-01-20)The loss-of-function of the inner nuclear membrane protein LAP1B (lamina-associated polypeptide 1, isoform B) causes muscular dystrophy and cardiomyopathy in humans. The function of LAP1B in muscle is still unknown. The ... -
Mekanosensitif İyon Kanalı Adayı Genlerin Astacus Leptodactylus Türünde Klonlanması ve İlgili Proteinlerin Fonksiyonel ve Yapısal Özelliklerinin Belirlenmesi
(Sağlık Bilimleri Enstitüsü, 2024-07-10)Cells respond to various mechanical stimuli like tension or osmotic pressure changes in the membrane. Mechanosensitive ion channels play an important role in mechanotransduction, which is the conversion of mechanical stimuli ... -
Molecular Propertıes of Crayfısh Potassıum Channels
(Sağlık Bilimleri Enstitüsü, 2021)Ergin, B., Molecular Properties of Crayfish Potassium Channels. Hacettepe University Graduate School of Health Sciences, Ph.D. Thesis in Biophysics, Ankara, 2021. Potassium channel family is the largest group in the ion ... -
Mycobacterium Tuberculosis Klinik İzolatlarında Yeni Antitüberküloz İlaçlar Olan Bedaquiline ve Delamanid'in MİK Değerlerinin ve Dirence Neden Olan Mutasyonların Saptanması
(Sağlık Bilimleri Enstitüsü, 2020)The purpose of this study is to detect the minimum inhibitory concentration (MIC) values of these novel drugs against to 101 resistant-M.tuberculosis clinical isolates with MGIT 960 automatized liquid culture system ... -
The Investıgatıon of Mechanoregulatory Role of Desmın
(Sağlık Bilimleri Enstitüsü, 2024)Desmin, a muscle-specific protein, shapes the network of intermediate filaments (IFs) in different types of muscles, such as cardiac, skeletal, and smooth muscles. Recent studies have elucidated cytoskeletal proteins' ... -
Yenilikçi Bir Smad Bildirici Yaklaşımı Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2024-01)Transforming growth factor-β (TGF-β) is a signaling molecule that has a regulatory role in many physiological processes such as cell differentiation, apoptosis, and regulation of immune response, especially wound healing. ...