Browsing Temel Tıp Bilimleri Bölümü by Issue Date
Now showing items 21-40 of 713
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Correlation Of In Vitro Fluconazole Susceptibility With Clinical Outcome For Severely Ill Patients With Oropharyngeal Candidiasis
(Univ Chicago Press, 1998)We investigated the correlation between in vitro susceptibility to fluconazole and clinical response in severely ill patients with oropharyngeal candidiasis treated with fluconazole. The study included 48 adult patients, ... -
Oxa-17, A Further Extended-Spectrum Variant Of Oxa-10 Beta-Lactamase, Isolated From Pseudomonas Aeruginosa
(Amer Soc Microbiology, 1999)Pseudomonas aeruginosa isolates 871 and 873 were isolated at Hacettepe University Hospital in Ankara and were highly resistant to ceftazidime (MIC, 128 mu g/ml). Each produced three beta-lactamases, with pIs of 5.3, 6.1, ... -
Antioxidant Action of the Antiarrhythmic Drug Mexiletine in Brain Membranes
(Japanese Pharmacological Soc, 1999)Mexiletine is a class Ib antiarrhythmic drug used in the treatment of ventricular arrhythmias. The Naf channel blocker mexiletine inhibits calcium influx in cells via decreasing reverse operation of the Na+-Ca2+ exchanger. ... -
Assignment of a Form of Congenital Muscular Dystrophy with Secondary Merosin Deficiency to Chromosome 1Q42
(Univ Chicago Press, 2000)We have previously reported an autosomal recessive form of congenital muscular dystrophy, characterized by proximal girdle weakness, generalized muscle hypertrophy, rigidity of the spine, and contractures of the tendo ... -
The Protective Effect Of Taurine Against Gentamicin-Induced Acute Tubular Necrosis In Rats
(Oxford Univ Press, 2000)Background. Taurine, which is the major intracellular free beta-amino acid, is known to be an endogenous antioxidant and a membrane-stabilizing agent. In this study, we wished to know whether taurine altered the concentration ... -
Mutations In Cgi-58, The Gene Encoding A New Protein Of The Esterase/Lipase/Thioesterase Subfamily, In Chanarin-Dorfman Syndrome
(Cell Press, 2001)Chanarin-Dorfman syndrome (CDS) is a rare autosomal recessive form of nonbullous congenital ichthyosiform erythroderma (NCIE) that is characterized by the presence of intracellular lipid droplets in most tissues. We ... -
In Vitro Susceptibility Testing Methods For Caspofungin Against Aspergillus And Fusarium Isolates
(Amer Soc Microbiology, 2001)We investigated the relevance of prominent reduction in turbidity macroscopically (MIC) and formation of aberrant hyphal tips microscopically (minimum effective concentration; MEC) in measuring the in vitro activity of ... -
Effects Of Aminoguanidine On Glomerular Basement Membrane Thickness And Anionic Charge In A Diabetic Rat Model
(2001)We investigated the effect of aminoguanidine (AG) administration on GBM thickness, glomerular heparan sulfate (HS) content, and urinary albumin and HS excretion in diabetic rats. After induction of diabetes, female Wistar ... -
The Changing Nature of Aminoglycoside Resistance Mechanisms and Prevalence of Newly Recognized Resistance Mechanisms in Turkey
(Blackwell Science Ltd, 2001)Objective, To determine the most frequently. occurring individual and combined resistance mechanisms, in Gram-negative bacteria resistant to any of the clinically available aminoglycosides in Turkey, and to compare these ... -
Meme Mikrokalsifikasyonlarının Bı-Rads (Breast Imaging Reporting and Data System) Kriterlerine Göre Değerlendirilmesi ve Yorumcular Arası Uyumun Araştırılması
(Sağlık Bilimleri Enstitüsü, 2001)EVALUATION OF BREAST MICROCALCIFICATIONS ACCORDING TO BI-RADS CRITERIA AND ASSESSMENT OF THE INTEROBSERVER AGREEMENT PURPOSE: Our purpose was to evaluate the positive predictive value for analysis of breast microcalcifications ... -
In Vitro Synergy Of Caspofungin And Amphotericin B Against Aspergillus And Fusarium Spp.
(Amer Soc Microbiology, 2002)We investigated the in vitro interaction of caspofungin and amphotericin B for clinical isolates of Aspergillus and Fusarium. Synergy tests were performed using the checkerboard method and following the NCCLS M38-P guidelines ... -
Mefv Gene Mutations In Familial Mediterranean Fever Phenotype Ii Patients With Renal Amyloidosis In Childhood: A Retrospective Clinicopathological And Molecular Study
(Oxford Univ Press, 2002)Background. Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurring attacks of fever and serositis. The definition of the mutated gene has allowed molecular diagnosis of the disease. ... -
Comparative Evaluation Of Disk Diffusion With Microdilution Assay In Susceptibility Testing Of Caspofungin Against Aspergillus And Fusarium Isolates
(Amer Soc Microbiology, 2002)We compared the disk diffusion and broth microdilution methods for susceptibility testing of caspofungin against Aspergillus (n = 78) and Fusarium (n = 22) isolates. Microdilution testing followed the NCCLS M-38P guidelines ... -
Effect of Antioxidants on The Immune Response of Helicobacter Pylori
(Blackwell Publishing Ltd, 2002)Antioxidants are substances capable of inhibiting oxidation. In chronic diseases, inflammatory response cells produce oxygen free radicals. Oxygen free radicals cause DNA damage, and this may lead to gene modifications ... -
In Vitro Activity Of Nystatin Compared With Those Of Liposomal Nystatin, Amphotericin B, And Fluconazole Against Clinical Candida Isolates
(Amer Soc Microbiology, 2002)We investigated the in vitro activity of nystatin and liposomal nystatin against 103 Candida isolates to determine the effect of both time and medium on MICs. We also compared the nystatin MICs with those of amphotericin ... -
Risk Factors For Breast Cancer In Turkish Women With Early Pregnancies And Long-Lasting Lactation - A Case-Control Study
(Taylor & Francis As, 2002)A hospital-based case-control study was carried out among 504 women with breast cancer and 610 controls to analyse the risk factors for breast cancer in Turkey. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) ...
