Başlık için Biyomühendislik listeleme
Toplam kayıt 64, listelenen: 7-26
-
Biyobozunur Plastik Polihidroksialkanoatların Bacillus Megaterium’da Genetik Mühendisliği Yoluyla Üretiminin Artırılması
(Fen Bilimleri Enstitüsü, 2021)Fossil fuel-derived plastic materials, have currently production and consumption values at increasing quantities, due to their lightness, easy malleability and economical reasons. Owing to their poor degradation rates and ... -
Böbrek Transplantasyonu Yapılacak PRA (Panel Reaktif Antikor) Pozitif Hastalarda Hla Haplotipleri İle İmmünofenotip İlişkisinin Araştırılması
(Fen Bilimleri Enstitüsü, 2022)The Human Leukocyte Antigen (HLA- Human Leucocyte Antigen) has an extremely complex morphology. This complex structure is an important factor that causes incompatibility between the patient and the donor, especially when ... -
Centella Asıatıca Bitki Özütü ile Kaplı Gümüş Nanopartikül İçeren Polimer Liflerin Yara İyileştirici Etkisinin in Vitro ve in Vivo Araştırılması
(Fen Bilimleri Enstitüsü, 2021)In this study, we synthesized functional silver nanoparticles (AgNPs) from silver ions using the therapeutic plant extract of Centella asiatica (CA). The formation of AgNPs coated with CA functional groups (CA-AgNPs) is ... -
Deselülerize Miyokard-Elastomer Yamaların Hazırlanması ve In Vitro Performanslarının İncelenmesi
(Fen Bilimleri Enstitüsü, 2021)Heart failure is the final stage of most cardiovascular diseases, such as myocardial infarction. Unlike other tissues such as bone and skin, heart tissue does not have the ability to regenerate and repair itself. This ... -
Development of Jak1 Sirna Medıated Nanotherapeutıcs for Non-Melanoma Skın Cancer Therapy
(Fen Bilimleri Enstitüsü, 2021-06)Non-melanoma skin cancer is one of the most common cancers with still no effective treatment. Due to the side effects observed after long and high dose treatments and acquired resistance to the chemotherapy drugs, different ... -
Doku İskelesi-Destekli Perfüzyon Biyoreaktör İşletim Parametrelerinin Preosteoblastların Üreme ve Osteojenik Farklılaşma Potansiyelleri Üzerine Etkilerinin Araştırılması
(Fen Bilimleri Enstitüsü, 2015-09-18)ABSTRACT INVESTIGATION OF EFFECTS OF SCAFFOLDSUPPORTED PERFUSION BIOREACTORS PROCESS PARAMETERS ON THE PROLIFERATION AND OSTEOBLASTIC DIFFERENTIATION OF PREOSTEOBLASTS Gizem AYDIN Master of Science, Department of ... -
Dolgulu Yatak Biyoreaktörde Mezenkimal Kök Hücre Üretiminin Araştırılması
(Fen Bilimleri Enstitüsü, 2020-08-20)In the thesis study, it was aimed to investigate mesenchymal stem cell production in packed bed bioreactor where non-woven polyester fiber matrices (NWPF) are used as carrier. In the preliminary studies, MC3T3-E1 mouse ... -
Epilepsi Tedavisinde Kullanılmak Üzere Fenitoin Yüklü Katı Lipid Nanopartiküllerin Sentezi ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2022)Epilepsy is a chronic neurological disease that affects 1% of the world's population and is characterized by spontaneous recurrent seizures. Common causes include pathogenic genetic variants in critical neuronal genes, ... -
Fonksiyonel Pet Nano Fiberlerin Üretilmesi ve Yara Örtüsü Olarak Kullanmak Üzere Modifiye Edilmiş Pet Fiberlere Protein Kaplı Gümüş Nanoparçacıkların Adsorpsiyonu
(Fen Bilimleri Enstitüsü, 2020)In this study, silver nanoparticles (S-AgNPs) coated with sericin were adsorbed on poly (ethylene terephthalate)-g-poly(hydroxyethylmethacrylate) (PET-g-HEMA) nanofibres and the use of the obtained material as wound dressing ... -
Geliştirilen Üç Boyutlu Böbrek Proksimal Tübül Modelinde Nefrotoksisite Değerlendirmesi
(Fen Bilimleri Enstitüsü, 2023)Acute kidney injury (AKI) is an important health problem causes the death of 2 million people worldwide every year with high morbidity and mortality. One of the important causes of AKI is drug-induced nephrotoxicity. After ... -
Göz İçi Tümör Radyocerrahisi İçin Göz Takip Sistemi ve Kalite Güvence Fantomunun Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023)Uveal malignant melanoma is the most common type of intraocular cancer in adults. Stereotactic radiosurgery applications are often used in the treatment of such tumors. In these radiation treatments performed with external ... -
Gıda Örneklerindeki Benzil Penisilin Hassas Tayinine Yönelik Moleküler Baskılanmış Polimer Temelli Optik Sensörlerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)Penicillin is one of the most commonly used beta antibiotics and has long been widely used in the treatment of various bacterial infections in humans, livestock, poultry and aquaculture. Therefore, the detection of these ... -
Gıda Ürünlerinde Mikrobiyal Bozulmaya Neden Olan Pseudeomonas Spp. Bakterisinin Yüzey Plazmon Rezonans (SPR) Temelli Biyosensör Kullanılarak Belirlenmesi
(Fen Bilimleri Enstitüsü, 2021)Nutrition is the intake of the nutrients they need in sufficient and balanced amounts in order to maintain healthy and quality living conditions. In order to meet the nutritional needs of the world population, which is ... -
Hasarlı Omurilik Onarımı İçin Hücre Destekli Enjekte Edilebilir İpek Fibroin Mikrotaşıyıcıların Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023-09)According to the data of the World Health Organization (WHO), spinal cord injuries affect between 250,000 and 500,000 people every year. In current clinical practice, there is no treatment method that can completely ... -
Havayolu Modellemesi Amaçlı Tasarlanan Mühendislik Ürünü 3B Hücre Kültür Sistemlerinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2022-06)Chronic airway diseases have a complex set of mechanisms in which environmental and genetic factors play a role. It is very important to study the molecular pathologies of these diseases and to establish suitable cellular ... -
Hücre Ölüm Yolaklarının Tespiti İçin Kağıt Tabanlı Biyosensör Tasarımı
(Fen Bilimleri Enstitüsü, 2021)The aim of the presented thesis, a paper-based biosensor design has been designed to be used in the detection of early (extrinsic pathway) and late (instrinsic pathway) stages of apoptosis. In the study, in order to ... -
Hücresizleştirilmiş Sığır Gözü Kası ve Pclkas Matriksi Kompozit Doku İskeleleriyle Göz Kası Rejenerasyonu
(Fen Bilimleri Enstitüsü, 2021)This study has been financially supported by TÜBİTAK under the project named "Extraocular Muscle Regeneration by Decellurized Bovine Extraocular Muscle and PCL-Extraocular Muscle Matrix Composite Tissue Skeleton" (1002 ... -
Investigating the Effectiveness of Wheat Starch and Polymeric Additives on the Production of Biomedical Thermoplastic Starch Composites
(Fen Bilimleri Enstitüsü, 2023)The presence of natural polymers as biomaterials has had a desirable efficacy on the development and progress of medical science research. Starch is a natural polymer that is abundant in nature, cost-effective, biodegradable, ... -
Islak Elektroeğirme ile Üretilen 3B Polimerik Yumaklarda Gözenek Boyutlarının Kontrolü
(Fen Bilimleri Enstitüsü, 2020-02-12)In this thesis, it is aimed to produce 3-dimensional (3D) polycaprolactone (PCL) scaffolds by wet electrospinning method with adjustable density and pore diameters. These scaffolds having adjustable pore diameters will ... -
İçeceklerde Bulunan Amaranth Tayinine Yönelik Sensörlerin Hazırlanması
(Fen Bilimleri Enstitüsü, 2021-06)Within the scope of the study, an Amaranth imprinted surface plasmon resonance (SPR) sensor was prepared for the determination of Amaranth, an azo group food dye used in beverages and various food products and reported to ...