Prematüre ve Kardiyak Cerrahi Geçirmiş İnfantlarda Nekrotizan Enterokolite İkincil Sindirim Kanalı Perforasyonu

Abstract

Necrotising enterocolitis (NEC) is the most common digestive tract disease primarily seen in premature infants. Congenital heart disease (CHD) is a risk factor for NEC in term infants. Mesenteric ischemia is claimed to be the cause of NEC in CHD. The aim of this study is to investigate the different features of patients with intestinal perforation secondary to NEC considering if they had cardiac surgery or not. A series of 20 cases with digestive tract perforation secondary to NEC, operated in Pediatric Surgery Department of Medical School of Hacettepe University between 1998 and 2012, were retrospectively investigated. The cases were investigated under two groups: Group 1, infants who had cardiac surgery and Group 2, infants without cardiac surgery. Demographic features, physical examinations, radiological findings, preoperative and postoperative course, medical/surgical treatments, and mortality rate of all cases were researched. Statistical analysis were done and statistical significance was p<0.05. Birth age, and birth weight of group 1 (n = 6) patients were smaller than and group 2 (n = 14) patients (p<0.05). Intrauterine growth retardation rate was higher in group 2 (p<0.05). More Group 1 patients had hypotension and hypoxia periods (p<0.05). Prostaglandin tratment and peritoneal dialysis was more frequent in Group 1 patients (p<0.05, (p<0.05). Mortality rate in Group 1 (83.33 %) is greater than Group 2 (21.42) (p<0.05) Intestinal perforation secondary to NEC is a disease of premature babies and infants who had cardiac surgery. It has higher mortality rate in infats who had cardiac surgery.