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Cyberknife® ve Varian RapidArc® TrilogyTM Cihazında Üç Boyutlu Uzaysal Fraksiyone Grid Terapi Doz Karakteristiklerinin Karşılaştırılması
(Kanser Enstitüsü, 2020-12)
. Lattice therapy is an innovative method to increase the effectiveness of radiotherapy by delivering a high dose to the target volume irradiated through small spaces in one or more fractions.In this study, we investigated ...
HER2 EKSPRESYONU OLAN MEME KANSERİ HÜCRELERİNDE ÖKARYOTİK ELONGASYON FAKTÖR-2 KİNAZ (eEF2K) AKTİVASYONUNUN ROLÜ
(Kanser Enstitüsü, 2021-06-22)
Continuous activation of HER2 leads to the deregulation of various biological responses such as cell proliferation, survival, and migration, and tumor growth. eEF2K is a protein kinase involved in the regulation of protein ...
Tüm Beden Işınlamalarında Farklı Tedavi Planlama Tekniklerinin Dozimetrik Olarak Karşılaştırılması
(Kanser Enstitüsü, 2021-02-10)
The purpose of Total Body Irradiation (TBI) in radiotherapy is to suppress the immune system of the patient by destroying bone marrow cells, prepare the host for bone marrow transplantation and enhance the antitumor effect. ...
Evaluation of Metadherin Expression in Breast Cancer
(Sağlık Bilimleri Enstitüsü, 2018)
Metadherin gene (MTDH/ AEG-1/ Lyric) encodes a 582- aminoacid protein, metadherin (MTDH), which is almost undetectable by immunohistochemistry in normal breast tissue. MTDH expression is markedly increased in breast cancer ...
Farklı Aktivasyon Basamaklarına İlerletilen Yardımcı T Hücrelerinde Adezyon ve Migrasyon Mekanizmalarının İncelenmesi
(Kanser Enstitüsü, 2020)
When different analog T lymphocyte profiles are examined in cancer and chronic infections, these cells can be divided into two subgroups with functional and dysfunctiononal characterization. Naive T lymphocytes which are ...
Çinko Katkılanmış Hidroksiapatit Nanoparçacıklarının Kanser Hücrelerinin Radyoduyarlılığına Etkisi
(Sağlık Bilimleri Enstitüsü, 2019-04-09)
Yedekçi, F.Y., Effect Of Zinc Doped Hydroxyapatite Nanoparticles On Radiosensitivity Of Cancer Cells, Hacettepe University, Graduate School of Health Sciences, Radiation Therapy Physics, Doctor of Philosophy Thesis, Ankara, ...
Prostat Kanserinde Tlr Agonistlerinin M1, M2 Makrofaj Polarizasyonunda Rolü
(Kanser Enstitüsü, 2019)
It is well known that inflammation is effective in the development of prostate cancer. Macrophages in the tumor microenvironment are either anti-inflammatory M2-type that help tumor growth or pro-inflammatory M1-type that ...
Aml Hastalarında Nkp30 Ve B7-H6, Gal-3, Bag6 Ekspresyon Düzeyleri İle Nk Hücre Sitotoksitesi Arasındaki İlişki
(Kanser Enstitüsü, 2020-01-10)
ABSTRACT
Aydın,B. The relationship between NKp30 and B7-H6, Gal-3, BAG6 expression levels and NK cell cytotoxicity in AML patients. Master of Science Thesis of Hacettepe University Graduate School of Health Sciences ...
Pankreas Kanserinde MUC1, MUC4, MUC16 Molekülleri ile Treg Hücreleri ve Epitelyal-Mezenkimal Transizyon Arasındaki İlişki
(Kanser Enstitüsü, 2020-08-14)
Pancreatic cancer has a poor prognosis due to its increased invasion and metastasis capacity. Transmembrane mucins normally have as their functions to protect the epithelial tissues but their expression level is has been ...
Mikrotübül İnhibitörlerinin Kanser Hücrelerinde Tehlike-İlişkili Moleküler Desen Düzeylerine Etkisinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2020)
Cancer cells are proliferate rapidly and uncontrolled. Chemotherapeutics such as vinorelbine and colchicine affect the cell cycle and DNA synthesis mechanism; they causes cells to be kept in the G2 / M phase by preventing ...
