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The Effect of Inducıble Costımulatory Lıgand (Icos-Lg) Expressıng Myeloıd Leukemıa Cells on Helper T Lymphocyte Actıvatıon and Exhaustıon
(Kanser Enstitüsü, 2015)
T cell exhaustion is characterized by progressive loss of cytokine production, decreased proliferation and resistance to reactivation especially upon continuous antigen stimulation. Despite being potent stimulators of ...