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Adjuvan Radyoterapi Planlanan Jinekolojik Kanserli Olgularda Radyoterapi Sırasındaki Kilo Değişiklikleri ve Organ Hareketlerine Bağlı Dozimetrik Değişikliklerin İncelenmesi
(Kanser Enstitüsü, 2014)
In this study, planned curative surgery and postoperative adjuvant radiotherapy (RT), 10 patient with gynecological tumors taken for planning purposes at the beginning of treatment with computed tomography (CT) taken in ...
All-Trans Retinoik Asit (Atra) ve 1Α,25-Dihidroksivitamin D3 (Vitamin D3) ile Uyarılan Akut Miyeloid Lösemi Hücrelerinin T Hücre Yanıtları Üzerine Etkisi
(Kanser Enstitüsü, 2014)
ATRA and D3 are the active metabolites of vitamin A and D, respectively. In this study, HL-60 myeloid leukemia cells were progressed through different maturation stages with ATRA, D3, LPS, and IFN-γ. For the determination ...
Expression and Functional Analysis of Ccrl2 Atypical Chemokine Receptor Variants on Breast Cancer Cells
(Kanser Enstitüsü, 2014)
The complex network of chemokines and chemokine receptors is regulated by atypical (decoy) chemokine receptors. Atypical chemokine receptors play role in the termination of inflammatory responses and CCRL2 is the newest ...
Expression of Toll Like Receptors in Lung Cancer and Investigating Their Effect on Apoptosis
(Kanser Enstitüsü, 2014)
Members of the Toll like receptors (TLRs) family play key roles in both innate and adoptive immune responses. TLRs proteins enable host to recognize a large number of pathogen associated molecular patterns such as bacterial ...
Meme Kanseri Hücrelerinde Pı-103 Inhibitörünün Aktive Reseptör Tirozin Kinaz Ekspresyonuna Etkisinin Incelenmesi
(Kanser Enstitüsü, 2014)
Oncogenic activation of PI3K/Akt/mTOR signaling pathway is frequently seen in breast cancer. Inhibition of signaling pathway by PI3K inhibitors, tyrosine kinase inhibitors and/or monoclonal antibodies causes increase in ...
Kolon Kanserli Hastalarda Interlökin 21 ve Interlökin32 Gen Ekspesyon Düzeyleri ve Metastaz Ilişkisi
(Kanser Enstitüsü, 2014)
Tumor microenvironment contains tumor cells, immune cells, stroma and stroma associated immune cells. This microenvironment of the immune system cells release chemokines and cytokines which play an important role in the ...
Reproductive Cancer Risk Factors Among Relatives of Cancer Patients Seeking Treatment in Hacettepe University Oncology Hospital
(Kanser Enstitüsü, 2014)
This study is an attempt to measure the frequency of specific gynecological cancer risk factors in female relatives of cancer patients. A cancer risk assessment questionnaire had been designed in the Department of Preventive ...