Browsing Kanser Enstitüsü Tez Koleksiyonu by Subject "costimulation"
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Selection and Charaterization of İmmune-Resistant Acute Myeloid Leukemia Cells
(Kanser Enstitüsü, 2024)Resistance to immunity is associated with the selection of cancer cells with superior capacities to survive inflammatory reactions. In the case of AML, immune reactions induce dynamic changes at genetic and epigenetic ... -
The Effect of Acute Myeloid Leukemia Cells Expressing PD-L2 Co-Stimulatory Molecule on Helper T Cell Activation
(Sağlık Bilimleri Enstitüsü, 2017-07-25)The binding of PD-1 to its ligands (PD-L1 and PD-L2) inhibits and/or regulates T cell responses. Myeloid leukemia cells can express both co-activatory and co-inhibitory molecules simultaneously. The function of PD-L1 in ...