• Psoriasiste Lipocalin 2 Spesifik Reseptörünün Immünohistokimyasal Olarak Saptanması 

      Sayar, Hamide; Özyurt, Kemal; Karabulut, Şefika; Doğan, Perihan Özlem; Seringeç, Nurten; Silay, Emin (2015)
      Amaç: Serum Lipokalin 2 (LCN2) seviyelerinin psoriasiste artmış inflamasyon için bir genel belirteç olduğu bilinmektedir. Bu çalışmada, LCN2’nin psoriatik lezyonlardaki reseptör düzeyini araştırmayı amaçladık. Yöntemler: ...
    • Serum 25-Hydroxy Vitamin D Status Is Not Related To Osteopenia/Osteoporosis Risk in Colorectal Cancer Survivors 

      Akıncı, Muhammed Bülent; Şendur, Mehmet Ali; Aksoy, Sercan; Yazıcı, Ozan; Yıldırım Özdemir, Nuriye; Köş, Tuğba; Yaman, Şebnem; Altundağ, Kadri; Zengin, Nurullah (Asian Pacific Organization Cancer Prevention, 2014)
      Background: The incidence of colorectal cancer increases with vitamin D deficiency as shown in recently published studies. In addition, prospective investigations have indicated that low vitamin D levels may be associated ...
    • Single Institution Experience on Cancer Among Adolescents 15-19 Years of Age 

      Yağcı Küpeli, Begül; Akyüz, Canan; Yalçın, Bilgehan; Varan, Ali; Kutluk, Tezer; Büyükpamukçu, Münevver (Turkish J Pediatrics, 2017)
      Adolescent cancers differ from other age groups in terms of cancer types, treatment and outcome. We aimed to present our institutional data on survival of certain types of cancer in adolescents. Hospital files were ...
    • Smoking Habits of Relatives of Patients with Cancer: Cancer Diagnosis in the Family is an Important Teachable Moment for Smoking Cessation 

      Hayran, Mutlu; Kılıçkap, Saadettin; Elkıran, Tamer; Akbulut, Hakan; Abalı, Hüseyin; Yüce, Deniz; Kılıç, Diclehan; Turhal, Serdar (Asian Pacific Organization Cancer Prevention, 2013)
      Background: In this study we aimed to determine the rate and habitual patterns of smoking, intentions of cessation, dependence levels and sociodemographic characteristics of relatives of patients with a diagnosis of cancer. ...
    • Smooth Muscle Cells Isolated from Thoracic Aortic Aneurysms Exhibit Increased Genomic Damage, but Similar Tendency for Apoptosis 

      Açılan, Ceyda; Serhatlı, Müge; Kaçar, Ömer; Adıgüzel, Zelal; Tuncer, Altuğ; Hayran, Mutlu; Baysal, Kemal (Mary Ann Liebert, Inc, 2012)
      Aortic aneurysms (AA) are characterized by structural deterioration leading to progressive dilation. During the development of AA, two key structural changes are pronounced, one being degradation of extracellular matrix ...
    • Stereotactic Re-Irradiation For Recurrent Or Second Primary Head-And-Neck Cancer 

      Ünal, İlhami; Cengiz, Mustafa (The Official Journal of Turkish Society for Radiation Oncology, 2018)
      Local recurrence after definitive radiotherapy for advanced head-and-neck cancer is observed in 30%– 60% of the patients. Surgical resection is possible in only about 25% of the cases. Re-irradiation for local recurrence ...
    • Successful Treatment of Intracaval and Atrial Extension of Wilms' Tumour by Chemotherapy 

      Berberoğlu, Semha; Akyüz, Canan; Büyükpamukçu, Münevver (British Med Journal Publ Group, 1996)
      A patient presenting with advanced Wilms' tumour was diagnosed as having inferior vena cava involvement with tumour thrombus extending up to the right atrium, and was treated with preoperative chemotherapy (vincristine, ...
    • Tamoxifen-Induced Tissue Factor Pathway Inhibitor Reduction: A Clue for an Acquired Thrombophilic State? 

      Erman, M.; Abalı, H.; Oran, B.; Haznedaroğlu, İbrahim C.; Canpınar, H.; Kirazlı, S.; Çelik, İ. (Oxford Univ Press, 2004)
      Background: Current understanding of hemostatic systems enables us to better explore the enigmatic pathobiology of tamoxifen (TAM)-induced thrombotic diathesis. We have therefore aimed to assess the hemostatic changes in ...
    • Targeted Therapies in Gastric Cancer and Future Perspectives 

      Yazıcı, Ozan; Şendur, M. Ali Nahit; Özdemir, Nuriye; Aksoy, Sercan (Baishideng Publishing Group Inc, 2016)
      Advanced gastric cancer (AGC) is associated with a high mortality rate and, despite multiple new chemotherapy options, the survival rates of patients with AGC remains poor. After the discovery of targeted therapies, research ...
    • The Association Between Body Mass Index and Immunohistochemical Subtypes in Breast Cancer 

      Şahin, Süleyman; Erdem, Gökmen U.; Karataş, Fatih; Aytekin, Aydın; Sever, Ali R.; Özışık, Yavuz; Altundağ, Kadri (Elsevier, 2017)
      Background:Body mass index (BMI) is defined as a poor prognostic factor in patients with breast cancer(BC). However, there are controversial results regarding the various effects of BMI on BC, hence the exactpathophysiology ...
    • The Relationship of Agmatine Deficiency with the Lung Cancer 

      Kapancık, Serkan; Çelik, V. Kenan; Kılıçkap, Saadettin; Kaçan, Turgut; Kapancık, Sercan (Akad Doktorlar Yayınevi, 2016)
      The polyamines are essential for rapidly growing cells. Polyamines is synthesized by two reactions which begin from arginine. The aim of this study is to examine the serum levels of the enzymes located in the putrescine ...
    • Transfection of Myeloid Leukaemia Cell Lines Is Distinctively Regulated By Fibronectin Substratum 

      Esendağlı, Güneş; Canpınar, Hande; Doğan, A. Lale; Akkaya, Munir; Kansu, Emin; Güç, Dicle (Springer, 2009)
      Gene transfer into haematopoietic cells is a challenging approach. The extracellular matrix component fibronectin has been known to modulate the cell cycle dynamics, viability and differentiation of leukaemia cells. Thus, ...
    • Ubiquitination And Regulation Of Aurka Identifies A Hypoxia-Independent E3 Ligase Activity Of Vhl 

      Hasanov, E.; Chen, G.; Chowdhury, P.; Weldon, J.; Ding, Z.; Jonasch, E.; Sen, S.; Walker, C. L.; Dere, R. (Nature Publishing Group, 2017)
      The hypoxia-regulated tumor-suppressor von Hippel-Lindau (VHL) is an E3 ligase that recognizes its substrates as part of an oxygen-dependent prolyl hydroxylase (PHD) reaction, with hypoxia-inducible factor α (HIFα) being ...
    • Vaccination Attitudes Among Patients With Cancer Receiving Chemotherapy 

      Akın, Serkan; Dizdar, Ömer; Özışık, Lale; Tanrıöver, Mine D.; Kamışlı, Songül; Erman, Mustafa; Hayran, Mutlu (Akad Doktorlar Yayınevi, 2016)
      Immunization against vaccine preventable diseases is an essential but mostly overlooked issue in oncology practice. We aimed to investigate the utilization of adult immunization recommendations and the perception of the ...