• Tamoxifen-Induced Tissue Factor Pathway Inhibitor Reduction: A Clue for an Acquired Thrombophilic State? 

      Erman, M.; Abalı, H.; Oran, B.; Haznedaroğlu, İbrahim C.; Canpınar, H.; Kirazlı, S.; Çelik, İ. (Oxford Univ Press, 2004)
      Background: Current understanding of hemostatic systems enables us to better explore the enigmatic pathobiology of tamoxifen (TAM)-induced thrombotic diathesis. We have therefore aimed to assess the hemostatic changes in ...
    • Targeted Therapies in Gastric Cancer and Future Perspectives 

      Yazıcı, Ozan; Şendur, M. Ali Nahit; Özdemir, Nuriye; Aksoy, Sercan (Baishideng Publishing Group Inc, 2016)
      Advanced gastric cancer (AGC) is associated with a high mortality rate and, despite multiple new chemotherapy options, the survival rates of patients with AGC remains poor. After the discovery of targeted therapies, research ...
    • The Association Between Body Mass Index and Immunohistochemical Subtypes in Breast Cancer 

      Şahin, Süleyman; Erdem, Gökmen U.; Karataş, Fatih; Aytekin, Aydın; Sever, Ali R.; Özışık, Yavuz; Altundağ, Kadri (Elsevier, 2017)
      Background:Body mass index (BMI) is defined as a poor prognostic factor in patients with breast cancer(BC). However, there are controversial results regarding the various effects of BMI on BC, hence the exactpathophysiology ...
    • The Relationship of Agmatine Deficiency with the Lung Cancer 

      Kapancık, Serkan; Çelik, V. Kenan; Kılıçkap, Saadettin; Kaçan, Turgut; Kapancık, Sercan (Akad Doktorlar Yayınevi, 2016)
      The polyamines are essential for rapidly growing cells. Polyamines is synthesized by two reactions which begin from arginine. The aim of this study is to examine the serum levels of the enzymes located in the putrescine ...
    • Transfection of Myeloid Leukaemia Cell Lines Is Distinctively Regulated By Fibronectin Substratum 

      Esendağlı, Güneş; Canpınar, Hande; Doğan, A. Lale; Akkaya, Munir; Kansu, Emin; Güç, Dicle (Springer, 2009)
      Gene transfer into haematopoietic cells is a challenging approach. The extracellular matrix component fibronectin has been known to modulate the cell cycle dynamics, viability and differentiation of leukaemia cells. Thus, ...
    • Ubiquitination And Regulation Of Aurka Identifies A Hypoxia-Independent E3 Ligase Activity Of Vhl 

      Hasanov, E.; Chen, G.; Chowdhury, P.; Weldon, J.; Ding, Z.; Jonasch, E.; Sen, S.; Walker, C. L.; Dere, R. (Nature Publishing Group, 2017)
      The hypoxia-regulated tumor-suppressor von Hippel-Lindau (VHL) is an E3 ligase that recognizes its substrates as part of an oxygen-dependent prolyl hydroxylase (PHD) reaction, with hypoxia-inducible factor α (HIFα) being ...
    • Vaccination Attitudes Among Patients With Cancer Receiving Chemotherapy 

      Akın, Serkan; Dizdar, Ömer; Özışık, Lale; Tanrıöver, Mine D.; Kamışlı, Songül; Erman, Mustafa; Hayran, Mutlu (Akad Doktorlar Yayınevi, 2016)
      Immunization against vaccine preventable diseases is an essential but mostly overlooked issue in oncology practice. We aimed to investigate the utilization of adult immunization recommendations and the perception of the ...