• Regulation of Tumor Angiogenesis by Ezh2 

      Lu, Chunhua; Han, Hee Dong; Mangala, Lingegowda S.; Ali-Fehmi, Rouba; Newton, Christopher S.; Ozbun, Laurent; Armaiz-Pena, Guillermo N.; Hu, Wei; Stone, Rebecca L.; Munkarah, Adnan; Ravoori, Murali K.; Shahzad, Mian M. K.; Lee, Jeong-Won; Mora, Edna; Langley, Robert R.; Carroll, Amy R.; Matsuo, Koji; Spannuth, Whitney A.; Schmandt, Rosemarie; Jennings, Nicholas B.; Goodman, Blake W.; Jaffe, Robert B.; Nick, Alpa M.; Kim, Hye Sun; Guven, Eylem Ozturk; Chen, Ya-Huey; Li, Long-Yuan; Hsu, Ming-Chuan; Coleman, Robert L.; Calin, George A.; Denkbas, Emir B.; Lim, Jae Yun; Lee, Ju-Seog; Kundra, Vikas; Birrer, Michael J.; Hung, Mien-Chie; Lopez-Berestein, Gabriel; Sood, Anil K. (Cell Press, 2010)
      Although VEGF-targeted therapies are showing promise, new angiogenesis targets are needed to make additional gains. Here, we show that increased Zeste homolog 2 (EZH2) expression in either tumor cells or in tumor vasculature ...