Başlık için Temel Tıp Bilimleri Bölümü Makale Koleksiyonu listeleme
Toplam kayıt 459, listelenen: 226-245
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Identification Of Two Novel Pnpla1 Mutations In Turkish Families With Autosomal Recessive Congenital Ichthyosis
(Turkish J Pediatrics, 2017)Autosomal recessive congenital ichthyosis (ARCI) is a group of inherited keratinization disorders that are characterized by abnormal epidermal keratinization. ARCI patients generally represent serious symptoms including ... -
Imetelstat (A Telomerase Antagonist) Exerts Off-Target Effects On The Cytoskeleton
(2013)Telomerase is a cellular ribonucleoprotein reverse transcriptase that plays a crucial role in telomere maintenance. This enzyme is expressed in approximately 90% of human tumors, but not in the majority of normal somatic ... -
Immunohistochemical Analysis Of Cd31, Cd36, And Cd44 Antigens In Human Omentum
(Saudi Med J, 2004)Objective: Milky spots in the human omental tissue are known to be consisting of lymphocytes, macrophages and mast cells. Our goal was to evaluate the relationship of lymphoid cells and macrophages with vasculature and ... -
Immunohistochemical Analysis Of Cd71, Cd98 And Cd99 Activation Antigens In Human Palatine And Nasopharyngeal Tonsils
(Saudi Med J, 2005)Objective: Tonsils (palatine and nasopharyngeal) are immunologically active tissues. Due to their anatomical location, they are considered to be the initial defense barrier against the antigens entering into the respiratory ... -
Immunohistochemical Investigation Of Endometrial Leukocytes In Implantation Period In Rats With Streptozotosin-Induced Diabetes
(Vesalius Univ Medical Publ, 2016)Our first aim was to determine the total leukocyte profile in implantation. Second aim was to detect the changes in uterine leukocyte profile in diabetes, a common accompanying disease. For this purpose 4 groups are formed ... -
Immunological Analysis Of A Cchfv Mrna Vaccine Candidate In Mouse Models
(2019)Development of new vaccine platforms against viral diseases is considered urgent. In recent years, mRNA constructs have attracted great interest in this field due to unique advantages over conventional gene transfer ... -
Impairment Of Lipophagy By Pnpla1 Mutations Causes Lipid Droplet Accumulation In Primary Fibroblasts Of Autosomal Recessive Congenital Ichthyosis Patients
(2019)Background: Autosomal Recessive Congenital Ichthyosis (ARCI) is a group of epidermal keratinization disorders. One of the disease-associated proteins, patatin-like phospholipase domain-containing protein-1 (PNPLA1), plays ... -
In Vitro Activity Of Caspofungin Compared To Amphotericin B, Fluconazole, And Itraconazole Against Candida Strains Isolated In A Turkish University Hospital
(Taylor & Francis Ltd, 2005)We investigated the in vitro activity of caspofungin compared to amphotericin B, fluconazole, and itraconazole against clinical strains of Candida spp. ( n = 239). Antifungal susceptibility tests were done in accordance ... -
In Vitro Activity Of Nystatin Compared With Those Of Liposomal Nystatin, Amphotericin B, And Fluconazole Against Clinical Candida Isolates
(Amer Soc Microbiology, 2002)We investigated the in vitro activity of nystatin and liposomal nystatin against 103 Candida isolates to determine the effect of both time and medium on MICs. We also compared the nystatin MICs with those of amphotericin ... -
In Vitro And In Vivo Fitness Costs Associated With Mycobacterium Tuberculosis Rpob Mutation H526D
(Future Medicine Ltd, 2017)Aim: There is controversy regarding the potential fitness costs of rifampicin (RIF) resistance-conferring mutations in the Mycobacterium tuberculosis (Mtb) rpoB gene. We characterized the pathogenicity of an Mtb RpoB H526D ... -
In Vitro Effects Of Phenytoin And Dapt On Mda-Mb-231 Breast Cancer Cells
(Oxford Univ Press, 2015)Voltage-gated sodium channel (VGSC) activity enhances cell behaviors related to metastasis, such as motility, invasion, and oncogene expression. Neonatal alternative splice form of Nav1.5 isoform is expressed in metastatic ... -
In Vitro Susceptibility Testing Methods For Caspofungin Against Aspergillus And Fusarium Isolates
(Amer Soc Microbiology, 2001)We investigated the relevance of prominent reduction in turbidity macroscopically (MIC) and formation of aberrant hyphal tips microscopically (minimum effective concentration; MEC) in measuring the in vitro activity of ... -
In Vitro Synergy Of Caspofungin And Amphotericin B Against Aspergillus And Fusarium Spp.
(Amer Soc Microbiology, 2002)We investigated the in vitro interaction of caspofungin and amphotericin B for clinical isolates of Aspergillus and Fusarium. Synergy tests were performed using the checkerboard method and following the NCCLS M38-P guidelines ... -
Increasing Carbapenem Resistance Due To The Clonal Dissemination Of Oxacillinase (Oxa-23 And Oxa-58)-Producing Acinetobacter Baumannii: Report From The Turkish Sentry Program Sites
(Microbiology Soc, 2008)A significant increase in carbapenem-resistance rates among Acinetobacter baumannii isolates collected in two Turkish medical centres was detected in the 2000-2006 period (20-60%) by the SENTRY Antimicrobial Surveillance ... -
Influence Of Previous Provisional Cementation On The Bond Strength Between Two Definitive Resin-Based Luting And Dentin Bonding Agents And Human Dentin
(Operative Dentistry Inc, 2007)This study evaluated the effect of two different types of provisional luting agents (RelyX Temp E, eugenol-based; RelyX Temp NE, eugenol-free) on the shear bond strengths between human dentin and two different resin-based ... -
Integration of Maternal Genome into the Neonate Genome through Breast Milk Mrna Transcripts and Reverse Transcriptase
(2012)Human milk samples contain microvesicles similar to the retroviruses. These microvesicles contain mRNA transcripts and possess reverse transcriptase activity. They contain about 14,000 transcripts representing the milk ... -
Invasive Mould Infections In Intensive Care Units: Epidemiology, Microbiologic Diagnosis And Antifungal Resistance
(2019)Invasive fungal infections present with a rising incidence and high morbidity and mortality rates. Among these infections are those due to moulds which draw particular attention per the diagnostic difficulties and higher ...