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Toplam kayıt 31, listelenen: 11-20
Selective Loss Of Function Variants In Il6St Cause Hyper-Ige Syndrome With Distinct Impairments Of T-Cell Phenotype And Function
(2019)
Hyper-IgE syndromes comprise a group of inborn errors of immunity. STAT3-deficient hyper-IgE syndrome is characterized by elevated serum IgE levels, recurrent infections and eczema, and characteristic skeletal anomalies. ...
The Association Between Vitamin D Levels And Infections In Patients With Primary Immunodeficiency
(2019)
Introduction: Vitamin D is a hormone responsible in the regulation of immune response. This study was designed to assess the relationship of vitamin D deficiency on the development of infections in patients with primary ...
Naturally Acquired Hepatitis a Antibodies After Haematopoetic Stem Cell Transplantation
(Cambridge University Press, 2011)
Haematopoietic stem cell transplant (HSCT) recipients lose immune memory of exposure to
infectious agents and vaccines accumulated throughout their lifetime and therefore need to be
revaccinated. We aimed to evaluate the ...
The Value of Flexible Bronchoscopy in Pulmonary Infections of Immunosuppressed Children
(Wiley, 2019)
Objectives
To demonstrate the value of flexible bronchoscopy (FB) and bronchoalveolar lavage (BAL) when determining causes of lung infection in immunocompromised children; to investigate differences in causes and radiological ...
Successful Outcome With Second Hematopoietic Stem Cell Transplantation in A Patient With IL-10R Deficiency
(Nature, 2016)
nterleukin-10 (IL-10) and IL-10 receptor (IL-10R) deficiencies, which are caused by loss of function mutations in the related genes, are primary immunodeficiencies that result in severe dysregulation of the immune system.1, ...
Human Intracellular Isg15 Prevents Interferon-Alpha/Beta Over-Amplification And Auto-Inflammation
(Nature Publishing Group, 2015)
Intracellular ISG15 is an interferon (IFN)-alpha/beta-inducible ubiquitin-like modifier which can covalently bind other proteins in a process called ISGylation; it is an effector of IFN-alpha/beta-dependent antiviral ...
Additional Diverse Findings Expand The Clinical Presentation of Dock8 Deficiency
(Springer/Plenum Publishers, 2012)
We describe seven Turkish children with DOCK8 deficiency who have not been previously reported. Three patients presented with typical features of recurrent or severe cutaneous viral infections, atopic dermatitis, and ...