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Allelic Variants in Genes Associated with Hereditary Periodic Fever Syndromes as Susceptibility Factors for Reactive Systemic AA Amyloidosis
(Nature Publishing Group, 2004)
We investigated the hypothesis that low-penetrance mutations in genes (TNFRSF1A, MEFV and NALP3/CIAS1) associated with hereditary periodic fever syndromes (HPFs) might be risk factors for AA amyloidosis among patients with ...
Highlights In Cellular And Molecular Mechanisms Of Allergic Diseases - Xxvth Congress Of The European Academy Of Allergology And Clinical Immunology In Vienna
(Karger, 2007)
This year, the annual congress of the European Academy of Allergology and Clinical Immunology was held on 10-14 June in Vienna. More than 6,000 delegates, practicing bench or bedside work or both, gathered from over 50 ...
Interleukin (Il)-12 And Il-23 Are Key Cytokines For Immunity Against Salmonella In Humans
(Univ Chicago Press, 2004)
Patients with inherited deficiency of the interleukin (IL)-12/IL-23-interferon (IFN)-gamma axis show increased susceptibility to invasive disease caused by the intramacrophage pathogens salmonellae and mycobacteria. We ...
Differential Biological Role Of Cd3 Chains Revealed By Human Immunodeficiencies
(Amer Assoc Immunologists, 2007)
The biological role in vivo of the homologous CD3 gamma and delta invariant chains within the human TCR/CD3 complex is a matter of debate, as murine models do not recapitulate human immunodeficiencies. We have characterized, ...
Life-Threatening Neurological Complications after Bone Marrow Transplantation in Children
(Nature Publishing Group, 2005)
Neurological complications may occur in BMT recipients (11-59%), frequently contributing to morbidity or mortality. They are the main causes of death in 10-15%. Life-threatening neurological complications were seen in 11 ...
Ifosfamide, Idarubicin, And Etoposide In Relapsed/Refractory Hodgkin Disease Or Non-Hodgkin Lymphoma: A Salvage Regimen With High Response Rates Before Autologous Stem Cell Transplantation
(Elsevier Science Inc, 2005)
To achieve long-term disease-free survival, high-dose therapy and autologous stem cell transplantation (ASCT) is the current standard approach in patients with relapsed or refractory Hodgkin disease (HD) or non-Hodgkin ...
A European Organization for Research and Treatment of Cancer - International Antimicrobial Therapy Group Study of Secondary Infections in Febrile, Neutropenic Patients with Cancer
(Univ Chicago Press, 2005)
Background. Neutropenic patients with cancer may develop several episodes of fever and infection during chemotherapy-induced myeloaplasia. Methods. To identify risk factors for secondary infectious episodes among patients ...
Tcr Dynamics in Human Mature T Lymphocytes Lacking Cd3 Gamma
(Amer Assoc Immunologists, 2003)
The contribution of CD3gamma to the surface expression, internalization, and intracellular trafficking of the TCR/CD3 complex (TCR) has not been completely defined. However, CD3gamma is believed to be crucial for constitutive ...
Risk Factors and Predictors of Outcome in Patients with Cancer and Breakthrough Candidemia
(Univ Chicago Press, 2001)
Hematogenous candidiasis adds substantially to the morbidity and mortality rates of patients with cancer. Little is known about the risk factors and outcome in patients with breakthrough (BT) candidemia while on systemic ...
Bacterial Infection Prevention After Hematopoietic Cell Transplantation
(Nature Publishing Group, 2009)