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Successful Bone Marrow Transplantation in a Case Of Griscelli Disease which Presented in Accelerated Phase with Neurological Involvement
(Stockton Press, 1999)
Griscelli disease (GD) is a rare disorder characterized by pigment dilution, immunodeficiency and occurrence of accelerated phase consisting of hemophagocytosis, pancytopenia and neurological manifestations, Allogeneic BMT ...
The Mutational Spectrum Of Ptpn11 In Juvenile Myelomonocytic Leukemia And Noonan Syndrome/Myeloproliferative Disease
(Amer Soc Hematology, 2005)
Germ line PTPN11 mutations cause 50% of cases of Noonan syndrome (NS). Somatic mutations in PTPN11 occur in 35% of patients with de novo, nonsyndromic juvenile myelomonocytic leukemia (JIMML). Myeloproliferative disorders ...
Myeloprotective Effect Of Short-Course High-Dose Methylprednisolone Treatment Before Consolidation Therapy In Children With Acute Myeloblastic Leukemia
(Wiley, 2005)
In our previous studies, short-course high-dose methylprednisolone (HDMP) has been shown to shorten the chemotherapy-induced neutropenic period by stimulating the CD34(+) hematopoietic progenitor cells in children with ...
Life-Threatening Neurological Complications after Bone Marrow Transplantation in Children
(Nature Publishing Group, 2005)
Neurological complications may occur in BMT recipients (11-59%), frequently contributing to morbidity or mortality. They are the main causes of death in 10-15%. Life-threatening neurological complications were seen in 11 ...
Benefit Of High-Dose Methylprednisolone In Comparison With Conventional-Dose Prednisolone During Remission Induction Therapy In Childhood Acute Lymphoblastic Leukemia For Long-Term Follow-Up
(Nature Publishing Group, 2003)
Eight-year event-free survival (EFS) was evaluated in 205 patients with acute lymphoblastic leukemia (ALL), to consider the efficacy of high-dose methylprednisolone (HDMP) given during remission induction chemotherapy ...