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Role of Endothelial Nitric Oxide Generation and Peroxynitrite Formation in Reperfusion Injury After Focal Cerebral Ischemia
(Lippincott Williams & Wilkins, 2000)
Background and Purpose-Reperfusion injury is one of the factors that unfavorably affects stroke outcome and shortens the window of opportunity for thrombolysis. Surges of nitric oxide (NO) and superoxide generation on ...
Reperfusion-Induced Oxidative/Nitrative Injury To Neurovascular Unit After Focal Cerebral Ischemia
(Lippincott Williams & Wilkins, 2004)
Background and Purpose-Use of thrombolysis in stroke is limited by a short therapeutic window because delayed reperfusion may cause brain hemorrhage and edema. Available evidence suggests a role for superoxide, NO, and ...