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Comparison Of Primary Human Cytotoxic T-Cell And Natural Killer Cell Responses Reveal Similar Molecular Requirements For Lytic Granule Exocytosis But Differences In Cytokine Production
(Amer Soc Hematology, 2013)
Cytotoxic lymphocytes, encompassing cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells, kill pathogen-infected, neoplastic, or certain hematopoietic cells through the release of perforin-containing lytic granules. ...
Molecular Diagnosis Of Shwachman-Diamond Syndrome Presenting With Pancytopenia At An Early Age: The First Report From Turkey
(Springer India, 2013)
A three-month-old boy presented with growth failure, skeletal abnormalities, otitis media and pancytopenia. Exocrine pancreatic insufficiency was confirmed by low levels of fecal elastase. He was diagnosed as Shwachman-Diamond ...
European Guidelines For Empirical Antibacterial Therapy For Febrile Neutropenic Patients In The Era Of Growing Resistance: Summary Of The 2011 4Th European Conference On Infections In Leukemia
(Ferrata Storti Foundation, 2013)
Owing to increasing resistance and the limited arsenal of new antibiotics, especially against Gram-negative pathogens, carefully designed antibiotic regimens are obligatory for febrile neutropenic patients, along with ...
Targeted Therapy Against Multi-Resistant Bacteria in Leukemic and Hematopoietic Stem Cell Transplant Recipients: Guidelines of the 4Th European Conference on Infections in Leukemia (Ecil-4, 2011)
(Ferrata Storti Foundation, 2013)
The detection of multi-resistant bacterial pathogens, particularly those to carbapenemases, in leukemic and stem cell transplant patients forces the use of old or non-conventional agents as the only remaining treatment ...