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Changing Etiological Trends In Male Precocious Puberty: Evaluation Of 100 Cases With Central Precocious Puberty Over The Last Decade
(Karger, 2015)
Background/ Aims: There are few studies in the literature that have evaluated the etiological factors in boys with central precocious puberty (CPP), and these studies are limited in terms of the sample size. In the present ...
Cobalamin C Disease Missed By Newborn Screening In A Patient With Low Carnitine Level
(Springer-Verlag Berlin, 2015)
Cobalamin C (CblC) disease is the most common inherited disorder of intracellular cobalamin metabolism. It is a multisystemic disorder mainly affecting the eye and brain and characterized biochemically by methylmalonic ...
Transformation Of Nonfunctioning Pancreatic Tumor Into Malignant Insulinoma After 3 Years: An Uncommon Clinical Course Of Insulinoma
(Sbem-Soc Brasil Endocrinologia & Metabologia, 2015)
A 62-year-old man admitted to our outpatient clinic with two months of recurrent life threatening hypoglycemia episodes. He was diagnosed as malignant insulinoma with multiple metastases of liver and peripancreatic lymph ...
Thyroid Hormone Resistance In Two Patients With Papillary Thyroid Microcarcinoma And Their Brafv600E Mutation Status
(Sbem-Soc Brasil Endocrinologia & Metabologia, 2015)
Resistance to thyroid hormone (RTH) is a rare autosomal dominant hereditary disorder. Here in, we report two patients with RTH in whom differentiated thyroid cancer was diagnosed. Two patients were admitted to our clinic ...
Weight-Sparing Effect Of Insulin Detemir: A Consequence Of Central Nervous System-Mediated Reduced Energy Intake?
(Wiley, 2015)
Insulin therapy is often associated with adverse weight gain. This is attributable, at least in part, to changes in energy balance and insulin's anabolic effects. Adverse weight gain increases the risk of poor macrovascular ...
Systemically Administered Brain-Targeted Nanoparticles Transport Peptides Across the Blood-Brain Barrier and Provide Neuroprotection
(Nature Publishing Group, 2015)
Although growth factors and anti-apoptotic peptides have been shown to be neuroprotective in stroke models, translation of these experimental findings to clinic is hampered by limited penetration of peptides to the brain. ...