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Disruption Of A Long-Range Cis-Acting Regulator For Shh Causes Preaxial Polydactyly
(Natl Acad Sciences, 2002)
Preaxial polydactyly (PPD) is a common limb malformation in human. A number of polydactylous mouse mutants indicate that misexpression of Shh is a common requirement for generating extra digits. Here we identify a translocation ...