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dc.contributor.advisorTÜRKYILMAZ, Meral Didem
dc.contributor.authorKIRBAÇ, Arzu
dc.date.accessioned2018-01-23T06:17:19Z
dc.date.available2018-01-23T06:17:19Z
dc.date.issued2018-01-05
dc.date.submitted2018-01-03
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dc.identifier.urihttp://hdl.handle.net/11655/4214
dc.description.abstractKırbaç, A., Speech Evoked Auditory Brainstem Responses: Normative Data Study, Hacettepe University Institute of Health Sciences, Doctor of Philosophy Thesis in Audiology and Speech Pathology Program, Ankara, 2018. Speech sound is a complex structure with rich harmonic components, dynamic amplitude modulations and rapid spectro-temporal changes. Simple stimuli such as tone-burst, click are insufficient in order to evaluate this complexity. At the brainstem level, auditory brainstem responses should be obtained using speech stimuli to assess the temporal and spectral encoding integrity of the speech stimulus. S-ABR is a valid and reliable tool that provides direct information on how the speech syllabus is coded by the auditory brainstem. It was planned in our study to determine the normative values specific to gender for the frequency domain display which includes the amplitude information of spectral peaks (F0, F1, F2_HF) with time domain display which includes 7 major (V, A, C, D, E, F, O) wave peak latency and amplitude information of the response by taking S-ABR records with artificial /da/ stimulus which has the duration of 40 ms from 30 healthy individuals between 18 and 35, whose native language is Turkish (15 males, 15 females). EEG data were collected from each individual in 5 sessions by using 32-channel headbox and data analyses were conducted in MATLAB software after the records. For each individual having participated in the study, amplitude and latency values of wave peaks were determined. Time domain and frequency domain wave forms were obtained from all participants and it was determined that speech sound are encoded earlier in brainstem in terms of time in females than it is done in males and gender is not effective in energy encoding of fundamental frequency and harmonics of the speech stimulus. It was considered that these data obtained shall form a basis for studies to be conducted for different groups.en
dc.description.tableofcontentsİÇİNDEKİLER ONAY SAYFASI iii YAYIMLAMA VE FİKRİ MÜLKİYET HAKLARI BEYANI iv ETİK BEYAN SAYFASI v TEŞEKKÜR vi ÖZET vii ABSTRACT viii İÇİNDEKİLER ix SİMGELER ve KISALTMALAR xi ŞEKİLLER xiii GRAFİKLER xiv TABLOLAR xv 1.GİRİŞ 1 2. GENEL BİLGİLER 3 2.1. İşitsel Sistemin Temel Yapı ve Fonksiyonu 3 2.1.1. Kulak 3 2.1.2. İşitsel Sinir Cevabı 4 2.1.3. Merkezi İşitsel Yollar 6 2.2. Konuşma Sesinin Temel Akustik Özellikleri 7 2.2.1. Fundamental Frekans (F0) 8 2.2.2. Harmonik Yapı 8 2.2.3. Formant Yapı 8 2.2.4. Periyodisite 8 2.3. Konuşma Sesi Uyaranına İşitsel Beyinsapı Cevabı (Speech Evoked Auditory Brainstem Response) 9 2.3.1. Uyaran ve Önemli Parametreler 11 2.3.2. Dalga Formu 14 2.3.3. S-ABR ‘nin Nöral Kaynakları 17 3. BİREYLER ve YÖNTEM 18 3.1. Bireylerin Seçim Kriterleri 18 3.2. Araçlar ve Yöntem 19 3.2.1. Odyolojik Değerlendirme 19 3.2.2. S-ABR Kayıtları 20 3.3. İstatistiksel Değerlendirme 24 4. BULGULAR 25 4.1. Demografik Bilgiler 25 4.2. S-ABR Değerlendirme 26 4.2.1. Time Domain Gösterime Ait Bulgular 26 4.2.2. Frequency Domain Gösterime Ait Bulgular 31 4.2.3. Dalga Piklerinin Belirlenme Oranları 33 4.2.4. Çalışma Verilerinin Amerikan Normatif Veri ile Karşılaştırması 35 5. TARTIŞMA 38 6. SONUÇ ve ÖNERİLER 46 7. KAYNAKLAR 48 8. EKLER 51 EK-1: Tez Çalışması ile İlgili Etik Kurul İzni EK-2: S-ABR Katılımcı Veri Formu EK-3: Kulaklığa Ait Teknik Bilgiler EK-4: Tüm Katılımcılara Ait Time Domain Dalga Formu 9. ÖZGEÇMİŞtr_TR
dc.language.isoturtr_TR
dc.publisherSağlık Bilimleri Enstitüsütr_TR
dc.rightsinfo:eu-repo/semantics/closedAccesstr_TR
dc.subjectKonuşma uyaranıtr_TR
dc.subjectişitsel beyinsapı
dc.subjectelektroensefalografi
dc.subjectnormatif veri
dc.titleKonuşma Sesi Uyaranına İşitsel Beyinsapı Cevabı: Normatif Veri Çalışmasıtr_TR
dc.typeinfo:eu-repo/semantics/doctoralThesistr_TR
dc.description.ozetKırbaç, A., Konuşma Sesi Uyaranına İşitsel Beyinsapı Cevabı: Normatif Veri Çalışması, Hacettepe Üniversitesi Sağlık Bilimleri Enstitüsü Odyoloji ve Konuşma Bozuklukları Programı Doktora Tezi, Ankara, 2018. Konuşma sesi zengin harmonik bileşenler, dinamik amplitüd modülasyonları ve hızlı spektro-temporal değişimlerin olduğu kompleks bir yapıdır. Bu karmaşık yapıyı değerlendirmek için tone-burst, klik gibi basit uyaranlar yetersiz kalır. Beyinsapı seviyesinde, konuşmanın temporal ve spektral kodlamasının bütünlüğünü değerlendirmek için konuşma sesi uyaranı kullanılarak işitsel beyinsapı cevaplarının elde edilmesi gerekmektedir. S-ABR, konuşma hecesinin, işitsel beyinsapı tarafından nasıl kodlandığı hakkında doğrudan bilgi sağlayan, geçerli ve güvenilir bir araçtır. Çalışmamızda 18-35 yaş arası, ana dili Türkçe olan 30 sağlıklı bireyden (15 kadın, 15 erkek) 40 ms durasyona sahip yapay /da/ uyaranı ile S-ABR kaydı yapılarak, cevabın 7 majör (V, A, C, D, E, F, O) dalga pik latans ve amplitüd bilgisini içeren time domain gösterimi ile spektral piklerin (F0, F1, F2_HF) amplitüd bilgisini içeren frequency domain gösterime ait, cinsiyete özgü normatif değerlerin belirlenmesi planlanmıştır. EEG verileri, 32 kanallı headbox kullanılarak her bireyden 5 oturumda toplanmış, veri analizleri kayıt sonrası MATLAB programında yapılmıştır. Çalışmaya katılan her birey için, dalga piklerinin amplitüd büyüklüğü ve latans değerleri belirlenmiştir. Time domain ve frequency domain dalga formları tüm katılımcılardan elde edilmiş, kadınlarda konuşma seslerinin, beyinsapında zamansal olarak daha erken kodlandığı, konuşma uyaranına ait fundamental frekans ve harmoniklerinin enerji kodlamasında ise cinsiyetin etkili olmadığı belirlenmiştir. Elde edilen bu verilerin, farklı gruplarla yapılacak çalışmalar için temel oluşturacağı düşünülmüştür.tr_TR
dc.contributor.departmentOdyolojitr_TR
dc.contributor.authorID205551tr_TR


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