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In Vivo Inhibition Of Lung Cancer By Grn163L: A Novel Human Telomerase Inhibitor
(Amer Assoc Cancer Research, 2005)
Differential regulation of telomerase activity in normal and tumor cells provides a rationale for the design of new classes of telomerase inhibitors. The telomerase enzyme complex presents multiple potential sites for the ...
Xeroderma Pigmentosum Complementation Group E Protein (Xpe/Ddb2): Purification Of Various Complexes Of Xpe And Analyses Of Their Damaged Dna Binding And Putative Dna Repair Properties
(Amer Soc Microbiology, 2005)
Xeroderma pigmentosum is characterized by increased sensitivity of the affected individuals to sunlight and light-induced skin cancers and, in some cases, to neurological abnormalities. The disease is caused by a mutation ...