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Toplam kayıt 7, listelenen: 1-7
Raloksifen'in Biyolojik Materyalden ve Farmasötik Preparattan Analizi İçin Gaz Kromatografisi-Kütle Spektrometrisi Yönteminin Geliştirilmesi ve Valide Edilmesi
(Sağlık Bilimleri Enstitüsü, 2012)
Raloxifene is selective estrogen modulator (SERM) drug which is used in the treatment of postmenopausal osteoporosis in women and used for doping in men. A new gas chromatography-mass spectrometry (GC-MS) method was developed ...
Özgün Heterosiklik Bileşiklerin Glutatyon Transferaz P1-1 İnhibitörleri Olarak Araştırılması ve İnsan Meme Kanser Hücreleri Üzerine Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2012)
The aim of this project is to
design inhibitors for GST P1-1 and test their effectiveness on breast cancer
cells. For this purpose benzoxazole, benzimidazole, benzothiazole derivative
compounds were synthesized. Recombinant ...
Dynamic Phosphometabolomic Profiling of Human Tissues and Transgenic Models By O-18-Assisted P-31 Nmr and Mass Spectrometry
(Amer Physiological Soc, 2012)
Next-generation screening of disease-related metabolomic phenotypes requires monitoring of both metabolite levels and turnover rates. Stable isotope O-18-assisted P-31 nuclear magnetic resonance (NMR) and mass spectrometry ...
Antioxidant and Cytotoxic Effects of Moltkia Aurea Boiss
(Acg Publications, 2012)
The water extract of M. aurea exhibited strong scavenging effect on 2,2-diphenyl-1-picrylhydrazil (DPPH), nitric oxide (NO) and superoxide (SO) radicals. The free radical scavenging effect of the extract was found comparable ...
The Proline-Rich Tetramerization Peptides In Equine Serum Butyrylcholinesterase
(Wiley-Blackwell, 2012)
Soluble, tetrameric, plasma butyrylcholinesterase from horse has previously been shown to include a non-covalently attached polyproline peptide in its structure. The polyproline peptide matched the polyproline-rich region ...
The Use And Importance Of Liposomes In Positron Emission Tomography
(Taylor & Francis Ltd, 2012)
Among different imaging modalities, Positron Emission Tomography (PET) gained importance in routine hospital practice depending on ability to diagnose diseases in early stages and tracing of therapy by obtaining metabolic ...
18O-Assisted Dynamic Metabolomics for Individualized Diagnostics and Treatment of Human Diseases
(2012)
Technological innovations and translation of basic discoveries to clinical practice drive advances in medicine. Today's innovative technologies enable comprehensive screening of the genome, transcriptome, proteome, and ...