Başlık için Temel Eczacılık Bilimleri Bölümü listeleme
Toplam kayıt 188, listelenen: 75-94
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Gadoterat Meglumin’in Bozunma Ürünlerinin Varlığında Yüksek Basınçlı Sıvı Kromatografisi ile Analizleri
(Sağlık Bilimleri Enstitüsü, 2023)Gadolinium contrast agents are chemicals used in magnetic resonance imaging. When injected into the body, gadolinium contrast agent enhances and improves the quality of magnetic resonance imaging. These substances are ... -
Glioblastoma Multiforme, Menenjiyom (Birincil) ve Metastaz (İkincil) Beyin Tümörlerine Ait Fenotiplerin Belirlenmesinde Kullanılacak Bütünleşik Omiks Analizler İçin Analitik Yöntem Geliştirilmesi ve Uygulanması
(Sağlık Bilimleri Enstitüsü, 2022)A thorough examination of intermediate molecular levels such as protein, metabolite, and lipid is required to establish direct causal and functional links between genotype and phenotype. Comprehensive metabolomics and ... -
Greater Efficiency Observed 12 Months Post-Implementation Of An Automatic Tube Sorting And Registration System In A Core Laboratory
(2016)Background Sample classification and registration have been recognized as important and time-consuming processes in laboratories. There is increasing pressure on laboratories to automate processes due to intense workload ... -
Growth Inhibitory Activity Of Ankaferd Hemostat On Primary Melanoma Cells And Cell Lines
(2017)Objective: Ankaferd hemostat is the first topical hemostatic agent about the red blood cell–fibrinogen relations tested in the clinical trials. Ankaferd hemostat consists of standardized plant extracts including Alpinia ... -
H2 Reseptör Antagonistlerinin Yeşil Hplc Ayırımı İçin Kemometrik Optimizasyon Yaklaşımı ve Famotidin İçeren Farmasötik Preparatlara Uygulanması
(Sağlık Bilimleri Enstitüsü, 2022)H2 receptor antagonists are often preferred in gastroesophageal reflux disease or in the treatment of gastric acidity disorders. In this thesis, an HPLC method for simultaneous analysis of H2 receptor antagonists, famotidine, ... -
HepG2, Caco-2 ve HT-29 Kanser Hücrelerinde 2D Jel Elektroforez ve MALDI-TOF/TOF-MS) ile Ankaferd Hemostat’ ın İn-Vitro Antineoplastik Etkisinin Proteomik Açıdan Araştırılması
(Sağlık Bilimleri Enstitüsü, 2019)One of the breakthroughs in life sciences has been accomplished through the completion of the human genome project. However, the compose of the entire genome map has also brought a tough task for scientists. This task is ... -
Hplc Method Development For The Simultaneous Analysis Of Amlodipine And Valsartan In Combined Dosage Forms And In Vitro Dissolution Studies
(Univ Sao Paulo, Conjunto Quimicas, 2010)A simple, rapid and reproducible HPLC method was developed for the simultaneous determination of amlodipine and valsartan in their combined dosage forms, and for drug dissolution studies. A C 18 column (ODS 2, 10 mu m, 200 ... -
Ht29 Ve K562 Kanser Hücrelerinde Protein ve Metabolitlerin Analizi Için Çeşitli Analitik Yöntemlerin Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2013)Cancer is one of the most dangerous fatal diseases threating the human being both economically and socially. Therefore, the studies are performed on molecular level to understand cancer on molecular level and prevent the ... -
Hupresin Retains Binding Capacity For Butyrylcholinesterase And Acetylcholinesterase After Sanitation With Sodium Hydroxide
(2017)Hupresin is a new affinity resin that binds butyrylcholinesterase (BChE) in human plasma and acetylcholinesterase (AChE) solubilized from red blood cells (RBC). Hupresin is available from the CHEMFORASE company. BChE in ... -
In Cellulo Examination Of A Beta-Alpha Hybrid Construct Of Beta-Hexosaminidase A Subunits, Reported To Interact With The Gm2 Activator Protein And Hydrolyze Gm2 Ganglioside
(2013)The hydrolysis in lysosomes of GM2 ganglioside to GM3 ganglioside requires the correct synthesis, intracellular assembly and transport of three separate gene products; i.e., the alpha and beta subunits of heterodimeric ... -
In Vitro Effects Of Rosmarinic Acid On Glutathione Reductase And Glucose 6-Phosphate Dehydrogenase
(Taylor & Francis Ltd, 2011)Context: Glutathione reductase (GR, NADPH:oxidized glutathione oxidoreductase, E. C 1.6.4.2) is a flavoprotein that catalyzes the NADPH-dependent reduction of oxidized glutathione (GSSG). GR is a crucial enzyme in the ... -
In Vivo And In Vitro Effects Of A Hif-1 Alpha Inhibitor, Rx-0047
(Wiley, 2008)HIF-1 alpha plays a major role in activating gene transcription and is important for maintaining homeostasis under hypoxic conditions. Since tumors are often in a hypoxic state, HIF-1 alpha is a potential target for the ... -
In Vivo Inhibition Of Lung Cancer By Grn163L: A Novel Human Telomerase Inhibitor
(Amer Assoc Cancer Research, 2005)Differential regulation of telomerase activity in normal and tumor cells provides a rationale for the design of new classes of telomerase inhibitors. The telomerase enzyme complex presents multiple potential sites for the ... -
Increased Levels Of Nitric Oxide, Cortisol And Adrenomedullin In Patients With Chronic Schizophrenia
(Karger, 2007)Objective: To investigate the levels of serum cortisol, dehydroepiandrosterone sulfate (DHEA-S), nitric oxide (NO) and adrenomedullin (AM) in schizophrenic patients. Subjects and Methods: Sixty-six male patients with chronic ... -
Indian Saffron - Turmeric (Curcuma Longa) Embedded Supermacroporous Cryogel Discs For Heavy Metal Removal
(2019)Cryogels are used in a variety of environmental and biotechnological processes. Cryogels are polymeric materials with large pores and open flow channels. Turmeric is a very popular spice, especially in India, which has ... -
Induction Of Telomere Dysfunction Mediated By The Telomerase Substrate Precursor 6-Thio-2'-Deoxyguanosine
(Amer Assoc Cancer Research, 2015)The relationships between telomerase and telomeres represent attractive targets for new anticancer agents. Here, we report that the nucleoside analogue 6-thio-2'-deoxyguanosine (6-thio-dG) is recognized by telomerase and ... -
Investigating the Structural Influence of Surface Mutations on Acetylcholinesterase Inhibition by Organophosphorus Compounds and Oxime Reactivation
(Elsevier Ireland Ltd, 2010)Organophosphates (OPs) exert their toxicity by inhibiting primarily acetylcholinesterase (AChE) and to a lesser extent butyrylcholinesterase (BChE). Binary mixtures of mammalian AChE and oximes of varying structure have ... -
Investigation Of Gelatinase Gene Expression And Growth Of Enterococcus Faecalis Clinical Isolates In Biofilm Models
(2019)Objectives: Enterococcus faecalis is the major reason for biofilm-related infections and it also interacts with Staphylococcus aureus in biofilms. Gelatinase (gelE) enzyme is an important virulence factor of E. faecalis ...