Başlık için Temel Eczacılık Bilimleri Bölümü listeleme
Toplam kayıt 188, listelenen: 167-186
-
Stereological Analysis Of Sciatic Nerve In Chickens Following Neonatal Pinealectomy: An Experimental Study
(2010)Background Although the injury to the peripheral nervous system is a common clinical problem, understanding of the role of melatonin in nerve degeneration and regeneration is incomplete. Methods The current study investigated ... -
Surface-Modified Bacterial Nanofibrillar Phb Scaffolds for Bladder Tissue Repair
(Taylor & Francis Ltd, 2016)The aim of the study is in vitro investigation of the feasibility of surface-modified bacterial nanofibrous poly [(R)-3-hydroxybutyrate] (PHB) graft for bladder reconstruction. In this study, the surface of electrospun ... -
Sülfür Metabolizmasında Yer Alan Metabolitlerin Miktar Tayini için LC-MS/MS Yönteminin Geliştirilmesi ve Valide Edilmesi
(Sağlık Bilimleri Enstitüsü, 2021-08)Sulfur metabolites play critical roles in cellular function. Changes in the levels and metabolism of sulfur compounds, were associated with cancer, which have led to the need to make precise, accurate and fast determination ... -
Synthesis and Investigation of Tyrosinase Inhibitory Activity of Some New Benzimidazole Derivatives
(Sağlık Bilimleri Enstitüsü, 2023)4 new 2-(4-(1H-benzimidazol-1-yl)phenyl)-3-(substitutedphenylamino)thiazolidin-4-one (2a-d) and 7 new 2-(4-(1H-benzimidazol-1-yl)phenyl)-3-(substitutedphenyl)thiazolidin-4-one (3a-g) were synthesized and their tyrosinase ... -
Synthesis of New 2-(N'-Allylidene-Hydrazino) Quinazolinones and 2-(4,5-Dihydropyrazolyl)-Quinazolinones and Their Antimicrobial and Antifungal Activity Screening
(Asian Journal Of Chemistry, 2014)Novel 2-[N'-(1,3-disubstituted-phenyl) allylidene] hydrazine-3-ethyl-3H-quinazolin-4-one (8) and 2-(3,5-disubstituted-phenyl-4,5-dihydropyrazol- 1-yl)-3-ethyl-3H-quinazolin-4-one (9) compounds have been prepared and tested ... -
The Effect Of Effort Test On The Levels Of Ischemia Modified Albumin, 7-Ketocholesterol And Cholestan-3Β , 5Α , 6Β -Triol And Their Role In The Diagnosis Of Coronary Artery Disease
(2019)Background Oxysterols have been shown to play a role in plaque formation while ischemia modified albumin (IMA) is widely accepted as an acute marker for ischemia. The effort test is one of the methods used to identify the ... -
The Effect of Low-Dose Methotrexate on Autologous Fat Graft Survival
(Tubitak Scientific & Technical Research Council Turkey, 2016)Background/aim: The survival of autologous fat graft tissue is dependent on various factors such as vascularization and inflammation. The aim of the present study was to evaluate the possible beneficial effects of low-dose ... -
The in Vitro and in Vivo Effects of Telomerase Substrate 6-Thio-2 -Deoxyguanosine
(Sağlık Bilimleri Enstitüsü, 2014)Telomerase mediated telomere targeted therapy represents a new approach in cancer therapy. In this study, I report that the nucleoside analogue 6-thio-2’-deoxyguanosine (6-thio-dG) is recognized by the telomerase ... -
The Proline-Rich Tetramerization Peptides In Equine Serum Butyrylcholinesterase
(Wiley-Blackwell, 2012)Soluble, tetrameric, plasma butyrylcholinesterase from horse has previously been shown to include a non-covalently attached polyproline peptide in its structure. The polyproline peptide matched the polyproline-rich region ... -
The Sublethal Effects Of (2,4-Dichlorophenoxy) Acetic Acid (2,4-D) On Narrow-Clawed Crayfish (Astacus Leptodactylus Eschscholtz, 1823)
(Inst Medical Research & Occupational Health, 2016)2,4-D is a widely used phenoxy herbicide, potentially toxic to humans and biota. The objective of the present study was to reveal short term sublethal effects of 2,4-D on narrow-clawed freshwater crayfish (Astacus leptodactylus ... -
The Trypsin-Inhibitory Efficiency Of Human Alpha(2)-Macroglobulin In The Presence Of Alpha(1)-Proteinase Inhibitor: Evidence For The Formation Of An Alpha(2)-Macroglobulin-Alpha(1)-Proteinase Inhibitor Complex
(Harwood Acad Publ Gmbh, Taylor & Francis Group, 1999)The inhibition of bovine pancreatic trypsin was studied at pH 7, 25 degrees C, using mixtures of purified human alpha(2)-macroglobulin (alpha(2)M) and alpha(1)-proteinase inhibitor (alpha(1)PI). The partitioning of the ... -
The Use And Importance Of Liposomes In Positron Emission Tomography
(Taylor & Francis Ltd, 2012)Among different imaging modalities, Positron Emission Tomography (PET) gained importance in routine hospital practice depending on ability to diagnose diseases in early stages and tracing of therapy by obtaining metabolic ... -
Trimetazidine Increases Cell Survival And Inhibits The Activation Of Inflammatory Response In Sodium Taurocholate-Induced Acute Pancreatitis
(Int College Of Surgeons, 2017)Objective: To evaluate the therapeutic effects of trimetazidine (TMZ) in an experimental acute pancreatitis (AP) model induced with sodium taurocholate (STC). Summary of Background Data: At present, AP is considered a ... -
Tıbbi Cihazlar
(Hacettepe Üniversitesi, 2017)Hastalıkların teşhis ve/veya tedavisinde farmakolojik, immünolojik veya rıvokimyasal mekanizmaları kullanmayan ama etkinin ortaya çıkmasına . nkal etki yoluyla yardımcı olan ürün grubuna tıbbi cihazlar adı verilmektedir. Global ... -
Use Of Hupresin To Capture Red Blood Cell Acetylcholinesterase For Detection Of Soman Exposure
(Amer Chemical Soc, 2018)Toxicity from acute exposure to nerve agents and organophosphorus toxicants is due to irreversible inhibition of acetylcholinesterase (AChE) in the nervous system. AChE in red blood cells is a surrogate for AChE in the ... -
Uv Spectrophotometric Method For Determination Of The Dissolution Profile Of Rivaroxaban
(Dissolution Technologies, Inc, 2014)Rivaroxaban is an oral anticoagulant that is the first available orally active direct Factor Xa inhibitor. In this study, a UV spectrophotometric method was developed for the determination of rivaroxaban content in ... -
Vinca soneri Koyuncu Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2023-09-08)Uyanır, E., Pharmacognostical investigation on Vinca soneri Koyuncu, Hacettepe University, Graduate School of Health Sciences, Pharmacognosy Programme, Master of Sciences Thesis, Ankara, 2023. Vinca soneri Koyuncu sp. nova ... -
Xeroderma Pigmentosum Complementation Group E Protein (Xpe/Ddb2): Purification Of Various Complexes Of Xpe And Analyses Of Their Damaged Dna Binding And Putative Dna Repair Properties
(Amer Soc Microbiology, 2005)Xeroderma pigmentosum is characterized by increased sensitivity of the affected individuals to sunlight and light-induced skin cancers and, in some cases, to neurological abnormalities. The disease is caused by a mutation ...