Kolelitiazisli Hastaların Beslenme Durumları ve Bazı Biyokimyasal Bulguların Değerlendirilmesi

Abstract

Yalcintas, EB. Analysis of Nutritional Status of Patients with Cholelithiasis and Some Biochemical Symptoms. Hacettepe University Institute of Health Sciences, Master of ScienceThesis in Dietetics Programme, Ankara, 2017. Cholelithiasis (gallbladder stones) is an issue that is of interest due to both its cost for the health care system and still unexplained etiology. The aim of this study is to define possible relations in gallbladder stone formation by evaluating anthropometric measurements, some biochemical findings and nutritional status of patients with cholelithiasis. This study was conducted with total 100 voluntary individuals between the ages of 20-65 who applied to Konya Eregli State Hospital, Department of General Surgery including 50 patients with cholelithiasis diagnosis (case; male:18, female:32) and 50 healthy individuals without cholelithiasis diagnosis (control; male:16, female:34).General information, nutrition status, physical activity levels of these individuals were recorded on a survey, their anthropometric measurements were made and their body mass index and waist / hip ratios were calculated.Average age of case group (male: 47.01 ± 4.17 years, female: 39.15 ± 4.23 years) was higher than that of control group (male, 30.53 ± 5.12 years, female, 32.51 ± 5.02 years) (p<0.05). Body mass index was average (male;29.7±3.5kg/m2, female;30.2±3.2kg/m2)in patient group and (male;27.1±3.4kg/m2, female;28.2±3.2kg/m2) in control group (p<0.05). Average waist circumference of patients in case group (male;97.6±15.8cm, female;103.2±15.1cm) was higher than that of control group (male;81.5±9.8cm, female;79.2±8.3cm)) (p<0.05). Total 52% of individuals in patient group and 32% of individuals in control group had sedentary or slightly active level of physical activity (p<0.05).Fasting blood sugar, total cholesterol and LDL cholesterol levels of individuals in case group were higher than that of control group (p<0.05). Significant linear relationship was found between dietary intake of energy (r=0.412, p<0.0001), percentage of fat (r=0.528, p<0.0001), and carbohydrate (g) (r=0.416, p<0.05) and formation of gallbladder stone (p<0.0001). Positive relationship was found with fat intake (g) (r=0.634, p<0.05) and negative relationship was found with dietary fiber intake. In this study, it was determined that the composition of the diet (energy, carbohydrate, % of carbohydrate, animal protein, fat,% of fat, fiber, soluble fiber, insoluble fiber, vitamins of B12 , magnesium), age, sex, BMI, blood sugar and blood lipids had an important effect on gallstone formation. In the prevention and treatment of cholelithiasis (gallbladder stone); healthy nutrition and diet therapy are important. Key Words: Cholelithiasis (gallbladder stone), nutrition, biochemical findings, anthropometric measurements