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3,5-Diamino İzoksazol Sübstitüye Triarilmetan Bileşiklerinin Sentezi
(Fen Bilimleri Enstitüsü, 2023)Isoxazoles are five-membered heterocyclic aromatic compounds. The given examples in the literature show that their synthesis and reactions have a wide importance. The reason for this is that the isoxazole compounds find ... -
A New Approach for the Determination of Trace Heavy Metals in Hair Dyeing Cosmetics
(Fen Bilimleri Enstitüsü, 2021)Although hair does not have a vital function in humans, it is an essential body component that affects appearance and self-confidence for both men and women. Cosmetic application using chemicals to change hair color is ... -
Alerjen Spesifik İmmunoglobulin E Tayini İçin Yüzey Plazmon Biyosensörlerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2022)Allergy is a mysterious chronic disease that causes the digestive system to be exposed to certain foods, the respiratory system to dust or pollen, or the skin to chemicals. Allergy is a very common disease affecting 10-20% ... -
Altın Nanopartiküller Kullanılarak Kortizol İçin Plazmonik Sensör Sinyalinin Seçici Yükseltilmesi
(Fen Bilimleri Enstitüsü, 2022)Cortisol is a steroid hormone released by the human body in response to psychological and physiological stress. Cortisol can affect almost every organ system such as nervous, immune, cardiovascular, respiratory, reproductive, ... -
Antiretroviral İlaç Baskılanmış Polimerik Nanopartiküllerin Hazırlanması, Karakterizasyonu ve Nazal Salınım Sistemlerde Kullanılması
(Fen Bilimleri Enstitüsü, 2023)The superior properties of molecularly imprinted polymers, such as stereospecific recognition, have recently brought their use in biomedical applications such as drug release. Nasal controlled release systems are an ... -
Antitrombosit İlaç Hedefleri için Bazı Fitokimyasalların İn Silico Taraması
(Fen Bilimleri Enstitüsü, 2023)Cardiovascular diseases (CVDs) are the leading cause of death globally, with an estimated 17.9 million deaths each year, a number that is predicted to increase more than 23.6 million by 2030.There are many antiplatelet ... -
Azot İçeren Borafenalen Temelli Organik Yarı İletken Modellerinin Teorik İncelenmesi
(Fen Bilimleri Enstitüsü, 2023)Organic semiconductors are the basic building materials of instruments used in many fields including opto-electronics, photo-electronics, thermo-electronics, transistors and solar cells and have an important place in ... -
Bağlanmış Küme Yöntemleri için Yerelleştirilmiş Doğal Orbitaller
(Fen Bilimleri Enstitüsü, 2023)It is known that Coupled-Cluster Singles and Doubles with Perturbative Triples, [CCSD(T)], which is used to calculate the molecular properties of chemical systems, provide very accurate results. The computational cost and ... -
Bakteri Ayrılması için Moleküler Baskılama Temelli Kriyojel Membranlar
(Fen Bilimleri Enstitüsü, 2023)Pseudomonas, an aerobic and gram-negative bacillus without fermenting properties, is widely found in soil, water and various moist environments. The type most commonly associated with disease in humans is Pseudomonas ... -
Bölgeye Özgü Bölgeye Özgü Glikolizasyon Analizlerinde Kullanılan Çarpışmalı Fragmantasyon Tekniklerinin Glikopeptit Tanımlama Performanslarının Kıyaslanması
(Fen Bilimleri Enstitüsü, 2023-06-14)Glycosylation is one of the most important post translational modifications of proteins and is involved in all kinds of biological and physiological processes. In order to have information about the identity of the ... -
Covıd-19 Tedavisi İçin Papain-Benzeri Proteaz (Plpro) İnhibitörlerinin İn Silico Yöntemler Kullanılarak Araştırılması
(Fen Bilimleri Enstitüsü, 2023)The new coronavirus pandemic, which started in December 2019 in Wuhan, China, affects the world. This disease, caused by the SARS-CoV-2 virus, was named COVID19. While 647 million people were caught worldwide; 6.6 million ... -
CuxBiyTez Nanofilmlerin Elektrokimyasal Potansiyel Altı Kodepozisyon Metodu ile Sentezi, Karakterizasyonu ve Potansiyel Güneş Pili Uygulamasının Araştırılması
(Fen Bilimleri Enstitüsü, 2023)The ternary copper-based chalcogenides CuxByCz (B = Sb, Bi; C = S, Se, Te) is an important class of materials for modern electronics, energy storage, and biomedical devices as they offer flexibility in composition, structure ... -
Darunavir Baskılanmış Phema Temelli Mikrokriyojellerin Hazırlanması ve Salım Kinetiğinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2022-02)Darunavir (D.V) is a powerful Antiretroviral drug used to treat infections with the human immunodeficiency virus (HIV). Acquired immunodeficiency syndrome (AIDS) is the most advanced stage of HIV infection. D.V is a synthetic ... -
Determination of Molecular Traces of Various Snake Venomes Using Proteomics and Glycomic Approaches Based on Mass Spectrometry
(Fen Bilimleri Enstitüsü, 2023-11)Viperidae snake species are distributed in a wide geographical region in Turkey. Specific proteome and glycoproteome composition profiles provide comprehensive information to study the venom’s biological function and ... -
Development of Polymeric Systems for Cabazitaxel Release
(Fen Bilimleri Enstitüsü, 2022-10-04)Cabazitaxel (CTZ) is a chemotherapy drug used to treat mCRPC patients. Bacterial cellulose (BC) has been combined with molecularly imprinted polymer (MIP) for anticancer drug delivery with controlled release. On surface-modified ... -
Dopamin 2 Reseptör Antagonisti Olarak Bazı Fitokimyasalların Antipsikotik Aktivitesinin Moleküler Doking Yöntemi ile Araştırılması
(Fen Bilimleri Enstitüsü, 2021)Schizophrenia is a psychotic disorder characterized by delusions, hallucinations, disturbances of perception, thought, and behavior. Schizophrenia is caused by overactivation of the dopamine D2 receptor. Currently, dopamine ... -
Elektrik Enerjisi Depolama Sistemi Olarak Tüm Krom ve Demir-Krom Redoks Akış Bataryaları İçin Elektrolit ve Elektrot Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2020)Due to their unique features of having a modular design for power and energy requirements of myriad applications, Redox Flow Batteries (RFB) are very promising among other energy storage systems. RFB Technology, provides ... -
Grubbs Katalizörlerinin Amin Fonksiyonlu Polistiren Desteğe İmmobilizasyonu ve Olefin Metatez Tepkimelerindeki Aktivitelerinin ve Etkinliklerinin Karşılaştırmalı Olarak İncelenmesi
(Fen Bilimleri Enstitüsü, 2023)The targeted reaction's activation energy can be lowered by metal catalysts, which play a role in controlling the mechanism of product formation. The recovery of these catalysts through isolation from the product mixture ... -
İnterpolimerik Komplekslerden Kontrollü İlaç Salımı
(Fen Bilimleri Enstitüsü, 2021)Controlled drug release is a technique used to provide the therapeutic effect in the desired time and drug delivery to the targeted area. Controlled drug release systems have many advantages, such as reducing possible side ... -
Karbon Bazlı Elektrotlar Yüzeyinde Vanadyum (III) / Vanadyum (II) Redoks Çiftleri İçin Bakır, Bizmut, Kalay ve Antimon Nanopartikül Yapısında Elektrokatalizör Biriktirilmesi
(Fen Bilimleri Enstitüsü, 2021-01-27)Vanadium redox flow batteries (VRAB); it is one of popular energy storage systems because it is used with renewable energy sources, has high charge-discharge effciency, low maintenance requirement and doesn’t contain harmful ...